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Articles Posted by Beckman Coulter

Stability of the Human Immunodeficiency Virus-1 Reverse Transcriptase Heterodimer

Published: June 27 2016

Abstract The characterization of a heteroassociating system is described in this article: The thermodissociation is studied using band sedimentation analysis; The electrostatic dissociation is studied using boundary sedimentation

Determination of Molecular Weight of Glycoproteins by Analytical Ultracentrifugation

Published: June 25 2016

Introduction Analytical ultracentrifugation is a classical technique that has played a critical role in laying the foundations for modern molecular biology. Among its achievements is the demonstration that proteins are macromolecules rather

The Solution Conformation of Novel Antibody Fragments Studied Using the Proteomelab XL-A Analytical Ultracentrifuge

Published: June 23 2016

Introduction One of the latest attempts to improve monoclonal antibodies in their use as radiolabeled diagnostic markers has involved the cross-linking of novel Fab’ fragments. It is expected that a relationship exists between the spacing

Analysis of Membrane Protein Dimerization by Sedimentation Equilibrium

Published: June 21 2016

Abstract Determination of the assembly state(s) of a membrane protein poses a difficult analytical problem. A powerful technique that is well adapted to meet this challenge is solution interaction analysis using analytical ultracentrifugation.

α-Chymotrypsin: Characterization of a Self-Associating System in the Analytical Ultracentrifuge

Published: June 19 2016

We have studied the dimerization of ?-chymotrypsin as an example of a typical self-associating system in order to show how such a reaction may be characterized. ?-Chymotrypsin has also been suggested as a model system to ensure

Short Column Sedimentation Equilibrium Analysis for Rapid Characterization of Macromolecules in Solution

Published: June 17 2016

Introduction Short column sedimentation equilibrium analysis offers many advantages for researchers wanting quick, sure characterization of the solution properties of macromolecules. Presented here is a list of when short column methods are an

Rapid Determination of Spectrophotometric Absorptivity by Analytical Ultracentrifugation

Published: June 15 2016

Introduction Spectrophotometric determination of protein concentrations is an important analytical tool for nearly all phases of protein drug development and manufacturing. Determinations of absorptivities (A0.1%) and molar extinction

Characterizing Insulin as a Biopharmaceutical Using Analytical Ultracentrifugation

Published: June 13 2016

Abstract Insulin is a well characterized drug used to treat diabetes. A large number of insulin formulations have been investigated in order to develop the optimum time delivery suited to patient needs. In addition, a number of insulin analogs

Characterizing RNA Nanoparticles by Analytical Ultracentrifugation

Published: June 11 2016

Abstract RNA  nanotechnology  is  gaining  in  popularity  due  to  its simplistic and rational design for creating nanostructures for applications in medicine and therapeutics.  RNA nanosquares were

The JXN-26 Enhances Workflows in Research and Bioprocessing

Published: March 31 2014

Beckman Coulter Life Sciences Brings Remote Control, Advanced Networking and Multiuser Management to Avanti High Performance Centrifuges Combining high performance and application versatility, Avanti JXN-26 centrifuges from Beckman Coulter Life

Automated RNA Sequencing Service from Beckman Coulter Genomics Provides Fast, High Quality Results

Published: April 4 2013

HiSeq* and Biomek platforms support a complete RNA-Seq solution     High throughput end-to-end RNA-Seq Service from Beckman Coulter Genomics includes customized project design, automated Illumina* TruSeq* RNA-Seq library construction

Beckman Coulter Life Sciences Introduces 14 New Antibodies

Published: November 29 2012

Labeled and Unlabeled Monoclonals Offer Specificity, Convenience, Flexibility   Beckman Coulter Life Sciences is expanding their flow cytometry portfolio with the addition of 14 new human monoclonal antibodies from Trillium Diagnostics

Biomek 4000 Workstation from Beckman Coulter Life Sciences Offers Adaptable, Intelligent Automation

Published: October 26 2012

Easy-to-use Platform Includes Icon-driven Software, Interchangeable Tools

Avanti J-26S High Performance Centrifuge Provides Enhanced Environmental, Safety Benefits

Published: August 9 2012

New 1-Liter Bottles Provide Sample Security The newly redesigned Avanti J-26S high performance centrifuge from Beckman Coulter Life Sciences combines important environmental benefits with increased BioSafety* features.  Coupling the J-26S

Beckman Coulter Life Sciences Introduces a 561 nm Laser Option for New Gallios Flow Cytometers at CYTO 2012

Published: June 25 2012

Range of Detected Dyes and Fluorescent Proteins Expands A 561 nm laser option, available for new 561 nm-laser ready Gallios flow cytometers from Beckman Coulter Life Sciences, will be on view at CYTO 2012, June 23-27 in booth 319 at the Congress

Beckman Coulter Introduces the Optima MAX-TL Tabletop Ultracentrifuge

Published: June 5 2012

Compact, Quiet Instrument Offers Optimum Efficiency The Optima MAX-TL tabletop ultracentrifuge, from Beckman Coulter Life Sciences, delivers optimum functionality and efficiency within a compact and quiet package.  Joining the Optima line

Kaluza 1.2 Cytometry Software from Beckman Coulter Provides World-class Speed, Enhanced Ease of Use

Published: January 17 2012

Software Instantly Analyzes Millions of Cells, Powers Gating in n-dimensions

Biomek P50 Pipette Tips from Beckman Coulter Provide Access to Samples in Deep and Narrow Labware

Published: January 2 2012

Fine Point Tip Design Enables Efficient Transfer of Small Volumes New Span-8 P50 Conductive Pipette Tips have been introduced by Beckman Coulter, Inc. to complement their existing P50 Non-Conductive Tip line. Both conductive and non-conductive ti

Optima X Series Ultracentrifuges from Beckman Coulter Offer Cutting-edge Usability and Communication Features Users Save Time, Reduce Costs, Increase Security

Published: November 9 2011

New Optima X Series preparative ultracentrifuges from Beckman Coulter, Inc. incorporate an array of contemporary technical features to enhance the user experience, increase productivity and reduce costs.  The new floor-model instruments also inc

Beckman Coulter Biomek P1000 Span-8 Pipette Tips Optimize Large Volume Transfers

Published: October 27 2011

Offered for Biomek NXP and FXP Liquid Handlers

Beckman Coulter Platforms Automate Stem Cell Differentiation

Published: October 13 2011

Process Increases Precision and Production, Decreases Costs

Beckman Coulter Announces the Allegra X-14 High-Throughput Centrifuge

Published: September 13 2011

120-V, Three-liter Refrigerated or Constant-Temperature Models  Boost Reliable Lab Performance The Allegra X-14, a new three-liter benchtop centrifuge from Beckman Coulter, Inc., accepts a variety of tubes and adapters to

Beckman Coulter Introduces the 1.6-liter Allegra X-30 Series Benchtop Centrifuge

Published: August 2 2011

Compact Instrument Offered with Convenient Application Packages      The medium capacity Allegra X-30 Series Benchtop Centrifuge from Beckman Coulter, Inc. is a versatile instrument. The compact, 18-inch-wide instrument is now available individuall

High-Performance Separation and ESI Module from Beckman Coulter Expands the Reach of Mass Spectrometry

Published: June 6 2011

Ultra-low Flow Range Reduces Ion Suppression and Increases MS Assay Sensitivity ORANGE COUNTY, CALIF. – (June 2, 2011) – The CESI 8000 High-Performance Separation-ESI Module with OptiMS Technology from Beckman Coulter, Inc. consists of the first c