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Beckman Coulter LS 6500 Articles

Image: Stability of the Human Immunodeficiency Virus-1 Reverse Transcriptase Heterodimer

Abstract The characterization of a heteroassociating system is described in this article: The thermodissociation is studied using band sedimentation analysis; The electrostatic dissociation is studied using boundary sedimentation...

Image: Determination of Molecular Weight of Glycoproteins by Analytical Ultracentrifugation

Introduction Analytical ultracentrifugation is a classical technique that has played a critical role in laying the foundations for modern molecular biology. Among its achievements is the demonstration that proteins are macromolecules rather...

Image: The Solution Conformation of Novel Antibody Fragments Studied Using the Proteomelab XL-A Analytical Ultracentrifuge

Introduction One of the latest attempts to improve monoclonal antibodies in their use as radiolabeled diagnostic markers has involved the cross-linking of novel Fab’ fragments. It is expected that a relationship exists between the spacing...

Image: Analysis of Membrane Protein Dimerization by Sedimentation Equilibrium

Abstract Determination of the assembly state(s) of a membrane protein poses a difficult analytical problem. A powerful technique that is well adapted to meet this challenge is solution interaction analysis using analytical ultracentrifugation....

Image: α-Chymotrypsin: Characterization of a Self-Associating System in the Analytical Ultracentrifuge

We have studied the dimerization of ?-chymotrypsin as an example of a typical self-associating system in order to show how such a reaction may be characterized. ?-Chymotrypsin has also been suggested as a model system to ensure...

Image: Short Column Sedimentation Equilibrium Analysis for Rapid Characterization of Macromolecules in Solution

Introduction Short column sedimentation equilibrium analysis offers many advantages for researchers wanting quick, sure characterization of the solution properties of macromolecules. Presented here is a list of when short column methods are an...

Image: Rapid Determination of Spectrophotometric Absorptivity by Analytical Ultracentrifugation

Introduction Spectrophotometric determination of protein concentrations is an important analytical tool for nearly all phases of protein drug development and manufacturing. Determinations of absorptivities (A0.1%) and molar extinction...

Image: Characterizing Insulin as a Biopharmaceutical Using Analytical Ultracentrifugation

Abstract Insulin is a well characterized drug used to treat diabetes. A large number of insulin formulations have been investigated in order to develop the optimum time delivery suited to patient needs. In addition, a number of insulin analogs...

Image: Characterizing RNA Nanoparticles  by Analytical Ultracentrifugation

Abstract RNA  nanotechnology  is  gaining  in  popularity  due  to  its simplistic and rational design for creating nanostructures for applications in medicine and therapeutics.  RNA nanosquares were...

Image: Beckman Coulter Genomics Receives Accreditation   from College of American Pathologists Will help the facility more quickly move findings from clinical trials into clinical use.

Beckman Coulter Genomics, a leading provider of DNA Sequencing Services announces today accreditation from the College of American Pathologists (CAP).   Furthering a long-standing commitment to delivering state-of-the-art sequencing...

Image: Beckman Coulter Life Sciences To Acquire Cytometer Maker Xitogen

Acquisition Will Broaden Product Offering, Provides Asian Operations Center Beckman Coulter Life Sciences has entered into an agreement to acquire Xitogen Technologies Inc. together with Cytojene Corporation. Xitogen, a flow cytometer developer...

Image: New Rotor from Beckman Coulter Life Sciences Increases Centrifugation Throughput and Flexibility

High Performance Unit Supports Full Range of Common Tubes...

Image: Beckman Coulter Life Sciences Features Automated Solutions and Systems for NGS, Screening, Cell Analysis at SLAS2014

Participating at a variety of levels and focused on the productivity and elegance of automated research, Beckman Coulter Life Sciences will be presenting workshops and posters and have a dynamic, interactive booth (#605) at this year’s meeting...

Image: Beckman Coulter Life Sciences Acquires Assets of ReaMetrix India Pvt. Ltd

Transaction Expands Flow Cytometry Line, Targets Routine Clinical Analyses Beckman Coulter Life Sciences, an innovator in life science research, has acquired the flow cytometry business assets of ReaMetrix India Pvt. Ltd, a Bangalore-based life...

Image: Stellan Hjertén Receives the Arnold O. Beckman Medal and Award at MicroScale Bioseparations Conference

University of Uppsala Professor Honored for Lifetime of Innovation Professor Wilhelm Einar Stellan Hjertén of the Institute of Biochemistry, Uppsala University in Sweden, received the Arnold O. Beckman Medal and Award, presented on...

Image: Beckman Coulter Life Sciences Introduces the DelsaMax Family of Products, Nanoparticle Research Breakthrough at Pittcon

Speed and Precision Increased in Biological, Chemical and Industrial Applications   DelsaMax particle analyzers measure the size and zeta potential of nanoparticles with groundbreaking speed and high precision.  Instruments in the...

Image: Beckman Coulter Life Sciences Introduces 14 New Antibodies

Labeled and Unlabeled Monoclonals Offer Specificity, Convenience, Flexibility   Beckman Coulter Life Sciences is expanding their flow cytometry portfolio with the addition of 14 new human monoclonal antibodies from Trillium Diagnostics...

Image: Biomek P50 Pipette Tips from Beckman Coulter Provide Access to Samples in Deep and Narrow Labware

Fine Point Tip Design Enables Efficient Transfer of Small Volumes New Span-8 P50 Conductive Pipette Tips have been introduced by Beckman Coulter, Inc. to complement their existing P50 Non-Conductive Tip line. Both conductive and non-conductive ti...

Image: Optima X Series Ultracentrifuges from Beckman Coulter Offer Cutting-edge Usability and Communication Features Users Save Time, Reduce Costs, Increase Security

New Optima X Series preparative ultracentrifuges from Beckman Coulter, Inc. incorporate an array of contemporary technical features to enhance the user experience, increase productivity and reduce costs.  The new floor-model instruments also inc...