Thermo Scientific Q Exactive™


Q Exactive™

The Thermo Scientific Q Exactive benchtop LC-MS/MS combines high-performance quadrupole precursor selection with high-resolution, accurate-mass (HR/AM) Orbitrap detection to deliver high performance and tremendous versatility. With innovative HR/AM Quanfirmation* capability, the Q Exactive* mass spectrometer makes it possible to identify, quantify and confirm more trace-level metabolites, contaminants, peptides and proteins in complex mixtures--in one analytical run.   
With a fast scan speed and multiplexing capabilities, the Q Exactive mass spectrometer is an outstanding detector for fast chromatography separation techniques. The superior quality of Q Exactive MS/MS data enables identification and quantitation of more compounds with greater confidence.   
The Q Exactive LC-MS/MS system not only offers broad screening capabilities but also excels at targeted quantitation experiments, making it a versatile addition to any laboratory. Fast, alternating positive-negative scan modes allow for the most comprehensive approaches, saving time during screening experiments.   
The benchtop system is ideally suited for drug metabolism, proteomics, environmental analysis, food safety, toxicology and clinical research applications.
Q Exactive™
Additional Specifications Max resolving power: 140,000 @ m/z 200   
Max scan rate: Up to 12 Hz at resolution setting of 17,500 @ m/z 200   
Mass accuracy    
Internal: 5000:1   
Polarity switching: One full cycle in < 1 sec (one full scan positive mode and one full scan negative mode at resolution setting of 17,500)   
Multiplexity: up to 10 precursors/scan   
Analog inputs    
One (1) analog input (0 - 1 V)   
One (1) analog (0 - 10 V)


  • Resolving power up to 140,000   
  • Maximum scan speed 12 Hz   
  • Intra-scan dynamic range > 5000:1   
  • Quadrupole mass filter   
  • Spectral multiplexing for enhanced duty cycle   
  • S-Lens ion source for increased sensitivity   


Q Exactive benchtop LC-MS/MS

Q Exactive benchtop LC-MS/MS

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Questions and Answers

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Question regarding C-trap filling

Dear Q Exactive community. I have a question regarding the C-trap filling. I am using the t-SIM-ddMS² mode for my analysis of peptides. To my sample I add isotopically labeled standard peptides. For that reason I use multiplexing (MSX count...

PM Maintenance

I have to PM this item and would like to know what i need to do.

exhaust connections

Hi, I'm a consulting Engineer and have a couple of questions regrading the connection of the forepump exhaust to the fume hood exhaut system for venting.  The installation guide says to run down then horizontal with the 1" hose...

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