Agilent Technologies 1200 Series Rapid Resolution


1200 Series Rapid Resolution

Increasing productivity, confidence in analytical results and cost-effectiveness are key objectives in today’s analytical laboratories. The Agilent 1200 Series Rapid Resolution LC (RRLC) system is designed to meet these challenges by delivering significantly faster results with higher data quality. On one system you can push RRLC performance to new limits and continue to run your conventional methods. Discover the plus in separation power and detection capabilities with new innovative system components, providing a new level of information about your sample for more informed decisions in shorter time.

* This item has been discontinued by the manufacturer.

1200 Series Rapid Resolution
Maximum Pressure 600 bar
Standard Flow Rate .05 to 5 ml/min
Additional Specifications Pump delay volume:    
Low delay volume configuration: 120 µL    
Medium delay volume configuration: 320 µL    
Standard delay volume configuration: 600 - 800 µL     
Flow rate range: 0.05 - 5 mL/min     
Maximum pressure: 600 bar    
Column dimensions: Length: 10 - 300 mm, ID: 0.05 - 8 mm    
Temperature range: 10 °C below ambient - 100 °C    
Temperature stability: 16 mm/sec (water / ACN gradient)    
Injection volumes: 0.1 - 40 µL (100µL and 1500 µL) without loop change, no overfill (drawn = injected volume)    
Maintenance and system test:    
Front access to all maintenance parts    
Maintenance instructions through multimedia CD-ROM    
Time for full system test (OQ/PV) < 4 hours    
Standard GLP features: Early maintenance feedback-EMF    
(tracks lamp burn time, usage, number of injections with limits and feedback messages)    
Extended GLP features (for systems inlcuding MWD SL, DAD SL or VWD SL Plus ):    
Data Recovery Card (DRC) for data security (prevents data losses in case of communication breakdowns)    
Radio Frequency Identification (RFID) for data traceability. (RFID tags for flow cells and UV lamp allow unambiguous traceability of measurement conditions)    
System control: Through local workstation software, client/server network data system and/or local handheld control module (1200 Series Instant Pilot). Default control: LAN / CAN.


  • Up to 60 % more resolution and up to 20 times faster compared to conventional LC    
  • New levels of UV detection – up to 5x more sensitivity with 1200 Series VWD SL Plus    
  • Full compatibility with existing HPLC methods    
  • Low carryover for uncompromised data quality    
  • Unlimited possibilities for automated method development    
  • Optimum support of LC/MS on narrow bore columns by low delay volume configuration (120 µL)    
  • Broad range of more than 140 RRHT columns 1.8 µm for wide applicability    
  • Easy, fast and secure method transfer from HPLC to RRLC by identical column chemistry of RRHT and HPLC columns    
  • 2000 samples/day on high throughput configuration, with Alternating Column Regeneration (ACR) using system setup with two pumps, two columns and a 2-Position/10-Port valve for alternating column switching    
  • Ultra fast universal detection with Agilent 1200 Series ELSD    
  • Agilent Lab Advisor Software helps you manage your lab for best chromatographic quality with intuitive diagnostic and monitor capabilities and alert functions to notify you of problems    
  • Typical Performance of the Agilent 1200 Series RRLC system    


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My self i am Krishna, I'm using the UPLC-Acuquity, my question is why we are using a gold color round type loop (it is placed before sample inject in to column) Any reason for specifically using gold color.

trying to compare to Waters UPLC

I am in the market for a LC/MS/MS system and just can not decide between the Agilent 1200RR and the Waters Acquity UPLC system. Any suggestions?

Micro Degasser

We have several Agilent 1200 systems equipped with micro degassers. Over the last couple years, many of them have started leaking out the front waste port. I know not to put the flow over 2.5 mL/min with the degasser inline. Why do we keep...

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