TAP Biosystems ambr™



ambr™ mimics the characteristics of classical bioreactors at microscale (10-15ml), by using cost effective, disposable micro bioreactors, controlled by an automated workstation. 
ambr enables the rapid evaluation of multiple bioreactor cultures at microscale, increasing productivity in cell line development with significant savings on materials and labour. 
The new ambr micro bioreactor in detail: 
Central to the system is the new ambr micro bioreactor – specifically designed to mimic the characteristics of a larger scale bioreactor. 
To learn more about the unique design and key features of the ambr micro bioreactor - take an interactive tour.


ambr workstation automates: 
The ambr workstation controls 24 or 48 disposable micro bioreactors, offering parallel processing and evaluation of multiple experiments in an automated microbioreactor benchtop system. 
  • Closed loop control of pH and DO with independent control of O2 and CO2 for each vessel 
  • Automated liquid handling for reactor set-up, feeds, base addition and sampling 
  • Easy installation into laminar flow hood allowing aseptic operation 
  • Optional integrated Vi-CELL® cell viability analysis 
ambr micro bioreactor system offers: 
  • A better tool for cell line selection and development - closely mimics the conditions of larger scale bioreactors) 
  • Simplified adoption of Quality by Design (QbD) principles for cell culture development 
  • Significant reduction in cost per experiment 
  • More experiments with less operator time for set up and clean down 
Applications include: 
  • Cell line selection 
  • Cell line stability 
  • Media feed strategies 
  • Process robustness experimentation in support of ‘quailty by design‘ studies 
  • Automation of DOE approaches to process optimisation 
ambr micro bioreactor system offers an accurate and cost-effective approach to replicating bioreactor conditions, and can be used as a microscale model for a wide range of upstream processes such as cell line selection and process optimisation.




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Hi We are currently using an AMBR microscale bioreactor system.  I am seeing lots of variability between duplicate bioreactors within the system.  Has anyone else had this issue?  It happens during each least two...

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