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Applied BioPhysics ECIS

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ECIS

Applied BioPhysics (ABP) automates tissue culture research by measuring the impedance of mammalian cells cultured on small electrodes. They provide electric cell-substrate impedance sensing (ECIS) instruments, disposable cultureware and optional accessories designed to work with ECIS instruments.         
         
The ECIS® line of instruments includes two different models that           
range in performance and capability, the ECIS® Z and the ECIS® Z.

Models

ECIS ZTheta
Attributes

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Additional Specifications The ECIS® ZΘ (theta) instrument provides researchers with our most advanced, automated, non-invasive instrument capable of monitoring cell behavior in real-time without the use of labels.

The ECIS® ZΘ measures the complex impedance spectrum (Z, R, C) of adherent cells growing on gold electrodes. The ECIS® ZΘ can be configured to address 16 or 96 independent electrodes pattered in various 1, 2, 8 and 96 well cultureware.

The instrument consists of a ZΘ system controller, 16 and/or 96 channel array station, computer and integrated software running on Windows 7 or Mac OS.

The ECIS® ZΘ includes the elevated field module to carry out automated wound-healing and electroporation experiments.
ECIS Z
Attributes

Edit Model

Additional Specifications The ECIS® Z instrument provides researchers with an advanced, automated, non-invasive instrument capable of monitoring cell behavior in real-time without the use of labels.

The ECIS® Z measures the simple impedance spectrum (Z) of adherent cells growing on gold electrodes. The ECIS® Z can be configured to address 16 or 96 independent electrodes pattered in various 1, 2, 8 and 96 well cultureware.

The instrument consists of a Z system controller, 16 and/or 96 channel array station, computer and integrated software running on Windows 7 or Mac OS.

The ECIS® Z includes the elevated field module to carry out automated wound-healing and electroporation experiments.

Features

ECIS® (Electric Cell-substrate Impedance Sensing) is a real-time, impedance-based method to study many of the activities of cells when grown in tissue culture. These include morphological changes, cell locomotion, and other behaviors directed by the cell’s cytoskeleton.            
           
Using impedance data at multiple AC frequencies the ECIS® model calculates time course changes in:           
• The barrier function (permeability) of the cell layer           
• The degree of constricted flow of current under the cells           
• The cell membrane capacitanc

Photos

  • ECIS ZTheta and 16W Array Station
  • ECIS Z and 16W Array Station
ECIS ZTheta and 16W Array Station

ECIS ZTheta and 16W Array Station

Manuals and Resources

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Instrument Documents

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Applied BioPhysics, Inc. applies the results of biophysical research to provide practical tools for cell research and drug discovery. ECIS™ or Electric...

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