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Thermo Scientific Q Exactive™ Hybrid Quadrupole-Orbitrap Mass Spectrometer

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Q Exactive™ Hybrid Quadrupole-Orbitrap Mass Spectrometer

Identify, quantify and confirm more compounds rapidly and with confidence using the Thermo Scientific™ Q Exactive™ Hybrid Quadrupole-Orbitrap Mass Spectrometer. This benchtop LC-MS/MS system combines quadruple precursor ion selection with high-resolution, accurate-mass (HRAM) Orbitrap detection to deliver exceptional performance and versatility. The Q Exactive Mass Spectrometer is equally useful for untargeted or targeted screening and a broad range of qualitative and quantitative applications in drug discovery, proteomics, environmental and food safety, clinical research and forensic toxicology.

Features

High-Confidence Results, Quickly         
         
  • HRAM and full-scan capabilities capture all sample data, all the time, enabling retrospective data analysis without need to re-run samples         
  • Resolving power up to 140,000 FWHM eliminates isobaric interferences, increasing confidence in results when analyzing samples in complex matrices         
  • Better than 1ppm mass accuracy in full-scan and all-ion fragmentation (AIF) modes ensures confident compound identification         
  • Fast scanning at 12hz and spectral multiplexing suited to UHPLC applications         
  • Rapid polarity switching maximizes information obtained         
  • AIF and multiple dissociation techniques—in-source CID and HCD—aid in compound identification         
  • Extended mass range to 6,000m/z enhances detection of singly charged small molecules and biomolecules         
  • More than four orders of magnitude intrascan dynamic range, along with femtogram-level sensitivity, allow detection of trace-level and high-abundance compounds in the same scan         
             
    Greater Confidence for Drug Discovery and Metabolism Studies         
             
  • Triple quadruple-equivalent ability to quantify parent compounds and metabolites along with identity confirmation provides greater throughput         
  • Fast HRAM Orbitrap technology eliminates interferences for high-confidence metabolite structural identification and large-scale profiling of metabolomics and lipidomics samples         
  • Fast scan-to-scan polarity switching in both MS and MS/MS modes maximizes metabolite detection and identification from a single injection         
             
    More Information for Superior Proteomics         
             
  • HCD yields superior fragmentation and higher-quality MS/MS spectra compared to CID, improving identifications         
  • High spectral quality and a wide dynamic range make it possible to identify and quantify proteins other instruments cannot find.         
  • Quan/qual capability make it easier to transition from proteomic discovery experiments to targeted protein quantification         
             
    Highly Specific Environmental and Food Safety Analyses         
             
  • Specificity exceeding triple quadruple Q-TOF or Q-Trap levels make this mass spectrometer the preferred quan/qual screening platform         
  • Data-dependent, full-scan MS/MS capabilities and HRAM data ensure the highest possible confidence in every identification         
             
    High-Confidence Quanfirmation for Clinical Research and Forensic Toxicology         
             
  • The combination of SRM and HRAM capabilities provides high-confidence quanfirmation of endogenous steroids, drugs of abuse and pain-management therapeutics with ease.         
             
    Application-Specific Software for Greater Throughput         
             
  • Thermo Scientific™ ExactFinder™, LCQuan™, Mass Frontier™, MetQuest™, MetWorks™, SIEVE™ and TraceFinder™ software are available to speed data analysis.
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    Q Exactive

    Q Exactive

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