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AMSbio PATHM2 Small Molecule Libraries

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PATHM2 Small Molecule Libraries

PATHM2 small molecule libraries share stem cell and medicinal chemistry expertise to allow you to modulate key cellular processes. Delivered ready-to-use PATHM2 small molecule libraries offer a convenient tool to screen the effects of proven compounds on your cells.   
   
  • Optimize your culture or differentiation process - Replace biologics, improve reproducibility: Screen our PATHM2-96 kit to identify accessory molecules that improve cell viability, proliferation or yields. All compounds are hand selected to address 'traditional' cascades that play a role in pluripotency maintenance or specific differentiation. Multiple agents were added to interrogate new and emerging networks/targets relevant to stem cell biology.   
       
  • Screen your disease model - Identify/confirm critical pathways and targets: Screen our PATHM2 kits to find disease state modulators as starting points for further refinement - all our compounds have drug/lead-like properties, good water solubility, bio-membrane permeability, activity/selectivity profile and potential for optimization. We also provide one-stop scale-up, medicinal chemistry, screening and development services.   
       
  • Study selected signaling pathways of interest - Identify key nodules, cross-talk, tune-up response: Screen our PATHM2 sets of modulators with differential pharmacology: agonsim, antagonism, partial modulation, reversible, allosteric, irreversible binding, sub-domain targeting and diverse pathway etiology.   
       
  • Find the optimal small molecule for your target - Selective/pan modulator, specific pharmacology: Screen our PATHM2 custom sets to identify more selective and potent small molecules to replace inferior but still commonly used ones (e.g. TGFΒ/BMP, ROCK, MEK/ERK, GSK3Β inhibitors, Wnt/Fz activators).
  • Features

  • Ready to use multi-well plate featuring key small molecule sets   
  • Ideal for stem cell differentiation, development biology and disease research   
  • Hand-selected for optimal pharmacological properties and clinical relevance   
  • Proven cellular activity for each compound
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    Formed in 1987 by Sandy Allan and Alex Sim the company’s first offices were in Madrid, Spain. Over the following three years further offices were...

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