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Irvine Scientific PRIME-XV® T Cell CDM

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PRIME-XV® T Cell CDM

Chemically-defined, animal component-free medium for T cell culture optimized to deliver consistent growth while maintaining T cell functionality and potency.   
   
PRIME-XV® T Cell CDM is the first commercially available chemically-defined, animal component-free medium for the expansion and cultivation of human T cells.    
   
Provides optimal performance including:   
  • Supports vigorous T cell growth in plates, cell culture bags, and in the G-Rex® while maintaining functionality   
  • Provides lot-to-lot consistency   
  • Removes the effects of undefined components on T cell phenotypes   
  • Supports polarization to targeted T cell types such as Th1 and T regulatory cells   
      
      
    Manufactured to facilitate transfer from research to clinic:     
  • Chemically-defined, animal component-free formula minimizes risks from adventitious agents   
  • Manufactured in compliance with cGMP regulations   
  • Traceability documentation provided including Certificates of Analysis, Certificates of Origin, and a Drug Master File (DMF) filed with the US FDA   
  • Extensive QA testing including functionality, sterility, and endotoxin   
  • Custom sizes and packaging available on request   
       
    High viability and expansion rates compared to non chemically-defined alternatives   
       
    CD3+ T cells derived from human peripheral blood mononuclear cells, were activated and cultured on treated polystyrene plates in PRIME-XV T Cell CDM or commercially-available xeno-free expansion media supplemented with IL-2. After 9 days, the viability and fold expansion of CD3+ T cells were quantified.   
       
    Storage:   
    Storage 2-8°C   
       
    Shelf Life:   
    12 months from the date of manufacture.
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