BellBrook Labs AptaFluor™



The AptaFluor™ SAH Methyltransferase Assay uses a natural occurring aptamer, or riboswitch, that selectively binds with SAH, the invariant product of methyltransferase reactions. The exquisite affinity and selectivity of the riboswitch combined with a positive TR-FRET signal enable screening and profiling of methyltransferases with unparalleled sensitivity.


  • Direct Detection of SAH with a TR-FRET Readout 
  • Ultra-Sensitive 
  • Stable 
  • Robust 
  • Simple Mix-and-Read 
  • Compatible with a Variety of MTase Acceptor Substrates 
  • Universal Assay – Use with Virtually Any Methyltransferase
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