Malvern Panalytical OMNISEC REVEAL



Molecular weight, intrinsic viscosity and numerous other parameters can be measured with OMNISEC REVEAL, the world’s most advanced integrated GPC/SEC multi-detector available. It can be added to any existing conventional GPC/SEC system or used in conjunction with OMNISEC RESOLVE to form a complete GPC/SEC solution, to offer comprehensive molecular characterization of synthetic and natural polymers, as well as proteins. 
OMNISEC REVEAL can be used to relate a polymer’s molecular properties to its bulk characteristics in a wide range of applications, from the packaging and paint industries to the manufacturing of food additives and pharmaceuticals. Its protein characterization capabilities can be used to study the effects of oligomerization, aggregation and conjugation on activity and efficacy in academic research and biopharmaceutical development.
Additional Specifications Dimensions (W, D, H) : 420, 640, 600 mm  
Weight : 40 kg  
Detector temperature range : 20 - 65 °C  
Software : OMNISEC software v10 (or later)  
Data acquisition rate : 100 Hz  
Patents : US20140060162A1 & EP2619543B1 "Modular capillary bridge viscometer" 
US20140144214A1 & EP2619544A1 "Automatically balanced capillary bridge viscometer" 
Detector 1 
Detector : Light scattering Measurement principle : RALS 90° angle, LALS 7° angle  
Light source : 50 mW, 640 nm laser Cell volume : 18 µL  
Dynamic range : 2500 mV  
Baseline noise : 107 g/mol Minimum quantifiable mass : 100 ng of 100kDa molecular weight polystyrene in THF Measurement principle : Light scattering (LALS or RALS) 
Measurement type 2 
Measurement type : Intrinsic viscosity Minimum quantifiable mass : 1 µg of 100kDa molecular weight polystyrene in THF Measurement principle : 4-capillary Wheatstone bridge 
Measurement type 3 
Measurement type : Concentration Minimum quantifiable mass : 100 ng of 100kDa molecular weight polystyrene in THF Measurement principle : Differential refractive index detection 
Operating environment 
Temperature : 15 °C - 30 °C 
Minimum computer specification : Windows 7 Professional 64 bit, 4th Gen Intel(R) Core I7 Processor (Quad Core HT, 3.4 GHz Turbo, w/ HD Graphics), 8 GB 1600 MHz DDR3 memory, 500 GB 3.5 inch SATA (7200 RPM) HDD, Full-HD monitor


  • Understand and control product performance of polymers, polysaccharides and proteins by measuring absolutemolecular weight, intrinsic viscosity, hydrodynamic radius, Mark-Houwink parameters, radius of gyration, branching, and co-polymer composition. 
  • Measure molecular weight as low as 200 Da or injection masses as low as 100 ng for characterization of samples which were previously unmeasurable using advanced detection. 
  • Improve separations and result accuracy with the column oven and temperature-controlled integrated detector compartment that minimizes inter-detector tubing 
  • Distinguish chemical changes by measuring absorbance across the full UV/Vis spectrum using the photodiode array 
  • Undertake a wide range of applications in different solvents thanks to Teflon and 316 stainless steel construction throughout 
  • Reduce instrument downtime and service costs with a novel self-balancing viscometer design with user-exchangeable capillaries 
  • Boost lab productivity with a novel self-balancing viscometer design with user-exchangeable capillaries.
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