Applied Biosystems 433A



The Model 433A System incorporates many state-of-the-art features that provide maximum flexibility, improved throughput, efficiency and functionality for peptide synthesis.


This instrument will no longer be available after June 30th, 2008. We will provide support for a period of five (5) years after the date of discontinuation.
Depth 53 cm
Height 66 cm
Width 79 cm
Weight 45 kg


Advanced peptide research demands uncompromised performance along with instrument and chemistry flexibility. The Model 433A System incorporates many state-of-the-art features that provide improved throughput, efficiency and functionality. For example, you can choose between Fmoc- and tBoc-based methods. If you have special synthesis needs, you can employ a variety of chemistry strategies to ensure optimal results.

Increase Throughput
The 433A system's unique feedback monitoring system increases through-put with more efficient synthesis of simple peptides. Complex peptides are synthesized with minimal trial-and-error and reagent waste. The SynthAssist® software and computer included with the system provides the power to take full advantage of the innovative feedback control technology.

Monitoring Capability
Intelligent dynamic feedback is activated where difficult reactions are encountered and can utilize any of the following cycle modifications automatically: extended deprotection and coupling, double coupling, capping, solvent exchange or addition, and /or interrupt synthesis at a safe step. Real-time monitoring trace is displayed on the computer screen.

Innovative Chemistries
Symmetric anhydride activation for couplings via ester bonds of hydroxyl groups. Useful for automated monomer loading to HMP resin when preloaded resin are not commercially available. Fmoc and tBoc combined strategy for cyclic and branched-chain peptides.


433A Peptide Synthesizer

433A Peptide Synthesizer

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Clogged Lines

I am able to go through the flushing procedure to remove all resin but when I attempt a flow test nothing comes out of the needles. Why can I flush my system but my flow test fails??

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Appl.Biosystems 433 A

Price: €€6,200.00