Hamilton Robotics Ion Exclusion


Ion Exclusion

A fast, versatile HPLC column packing material, Hamilton PRP-X300 columns rapidly and easily separate closely related alcohols and organic acids without column heating. The sulfonated poly(styrene-divinylbenzene) support separates samples by a mixed mode mechanism.

The three separation modes are:

1. Hydrogen Bonding
The attraction and retention of sample compounds by the negatively charged sulfonate group

2. Reversed Phase
The interaction and retention of the sample compounds by the nonpolar polymeric support

3. Ion Exclusion
The process in which ionized samples are excluded from the pores of the support and elute first, while the non-ionic compounds elute later


  • One particle size: 7 ┬Ám.
  • Three column internal diameters: 1.0 to 4.6 mm.
  • Two column materials: 316 stainless steel and PEEK
  • Analytical and semiprep/preparative guard columns.


Ion Exclusion

Ion Exclusion

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