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November 18, 2013


 Product Resources

 Top 4 Signs That You Should Service or Replace Your Microplate Reader

  1. Misalignment of the microplate transport system with the measurement optics is one of the most common problems to occur in microplate readers over time. The easiest way to diagnose this problem is to fill each well of a 96- or a 384- well plate with the same concentration of fluorescein (or another colormetric dye). Measure the entire plate. If there is a trend of increasing or decreasing values across the plate, and if the same trend is seen after the plate is turned 180 degrees, then the instrument may be misaligned and the manufacturer should be contacted for service.
  2. When users need a new feature, a new detection mode, or a new technology that is not found in their current instrument, it’s usually time to replace their current instrument.
  3. The instrument’s software is out of date and an update is not available for the user’s current system.
  4. Wear and tear on the reader, such as degraded filters or worn out motors and belts, can also mean it’s time to replace or service the instrument.

Tip: One way to keep a microplate reader going is to have an annual QCPM (Quality Control Preventative Maintenance) check.

Top 8 Questions You Should Ask When Buying a Microplate Reader

  1. How many read modes are offered? Multiple read modes offer greater flexibility and value than single read modes for those working with, or considering the addition of, various assay platforms.
  2. What kind of detection technology is used? Monochromator-based detection offers flexibility, convenience and spectral scanning; while filter-based detection is characterized by precise sensitivity and may often switch rapidly between distinct wavelengths for kinetic assays. Hybrid detection systems combine both technologies in one compact unit for the utmost in flexibility and sensitivity.
  3. Is it upgradeable? If so, can the upgrade be installed on-site, or must it be shipped back to the factory? On-site installations reduce overall downtime, and often the technician is available to answer questions or conduct training.

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 Product of Interest

ELGA provides an innovation solution for your ultra-pure water needs

The PURELAB flex combines ease of use with the accurate delivery of pure and ultra-pure water from a single system.

  • Tap to ultrapure water
  • Absolute water purity up to 18.2 M?-cm
  • Ergonomic handset shows your essential water purity information
  • Real Time TOC monitoring
  • Unique choice of water dispense options

Visit the Elga website to read more about the PURELAB flex.

captair flex Ductless fume hoods

Designed to protect users during applications that emit vapors and/or chemical particles, the CaptairFlex line of ductless fume hoods offer a level of performance that ensures your safety while offering an environmentally-friendly alternative to traditional systems.
Erlab's "flex technology" provides the user with a wide range of possibilities in the filtration stack above the fume hood. This allows you to carry out a variety of applications in your laboratory.

The high containment and filtration performance of this technology delivers a high degree of protection (AFNOR NF X 15-211: 2009 standard, class 1 and class 2).

Visit the captair website to learn more about their line of Ductless Fume hoods.

 Featured Questions and Discussions

Plenty of discussions are happening on LabWrench all the time. We have many questions come in daily from users that are seeking advice from fellow users and lab professionals on LabWrench. Can you help any of these users find the answers they are looking for?

Agilent Cary 60 problem
How can I resolve error 9;9328SEQ;E9328 fatal initialisation on my Agilent Cary 60 spectrophotometer?  Provide directions.

Parr 6400 Calorimeter: Loud hissing on O2 Fill
Troubleshooting our Parr 6400 - Concerned with loud hissing during oxygen fill cycle (doesn't happen every run).  Can the O2 flow restrictor (part 527VB) be the cause of this?  Respond to this member.

Beckman Coulter ACL TOP 500 CTS tube compatibility question
I'm interested in running some very small tubes on the instrument - MiniCollect 450413 tubes to be exact.  Does anybody know of an adapter or some other way that I could run these tubes without manipulation?  Respond to this member.

View all Questions and Discussions on LabWrench

 Have a Question ??

 Sponsor of the Week

Thank you BMG LABTECH for sponsoring the Microplate Readers category on LabWrench

BMG LABTECH is a leading developer and global manufacturer of microplate reader instrumentation with a wide range of measurement methods. Microplate readers are used in the pharmaceutical and biotech industries, as well as in academic research establishments, for both basic research analysis and High Throughput Screening. BMG LABTECH focuses solely on microplate readers and offers the most diverse selection of optical detection systems in conjunction with integrated liquid handling equipment.

Visit the BMG LABTECH website to learn more about their Microplate offerings.

 Product Resources

Erlab’s Captair Pyramid…a light-weight, portable isolation chamber for use in forensics investigation
The Captair Pyramid is designed to protect the user during the investigation and transport of biological samples. It is a multi-function disposable glove box made of high-quality transparent PVC. Assembled in a few seconds, it can be used anywhere. The slanted shape of the enclosure provides an ergonomic working position for the user. Light, mobile and disposable, it is an ideal protection tool for use in the laboratory or in the field.  Read more.

New Digital Stirring Hot Plate features direct sample temperature control and precise temperature ramping
Torrey Pines Scientific, Inc. announces its NEW EchoTherm™ Digital Stirring Hot Plate for use in chemical, pharmaceutical, environmental, biochemical, and other laboratories where simple, reproducible, and accurate sample preparation and experimentation are a must. Read more.

New Serological Pipettor Improves Liquid Handling Productivity
INTEGRA announces the launch of the new PIPETBOY acu 2 serological pipettor. The second generation of PIPETBOY acu is equipped with the latest technology providing a significant increase in pipetting speed and a sizeable weight reduction making using the instrument over extended periods of time even more comfortable. These two new developments help improve your productivity and deliver an enhanced ergonomic pipetting experience. Read more.

View all news articles on LabWrench

 Questions from the Vault

We have so many questions filling our forums that sometimes questions can be missed and go without answers. Can you help us provide answers for these users with unanswered questions?

Troubleshooting a Beckman Coulter AD 340C Microplate Reader
How can I remove the upper part of the reader to inspect the microplate holder? I am getting 2 error messages upon start-up:
E4:  Plate error
E20: Fork error
Provide assistance

EL404 - Inadequate fluid flow error message on BioTek EL 404 Auto MicroPlate Washer
I am receiving an inadequate fluid flow message. Changing tubing temporarily fixed error message, but it has returned.  Any suggestions?

Fluorescence Polarization using 355 and 460 w/ X5 on Perkin Elmer VICTORY X
We are doing Fluorescence Polarization using 355 and 460 and getting an error that the light source is not strong enough.  It is a new bulb and we can do FP at other wavelengths and get no error.  Your thoughts?

View all Questions and Discussions on LabWrench

 Upcoming FREE Webinar

Innovations in Chromatography Analysis

Thursday. Nov. 21, 2013
12:00 - 1:30 PM EST
 Register Now!

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