96 Well Microplates with 3D Epoxy Surface for Covalent Binding of Biomolecules
Greiner Bio-One, a technology partner for the diagnostic and pharmaceutical industry, has developed 96 well microplates with a 3D epoxy surface in collaboration with its longstanding cooperation partner PolyAn. The 3D epoxy surface is the ideal platform for covalent binding of proteins, peptides, DNA and oligonucleotides. 
The three-dimensional functional matrix allows the development of covalent binding of nucleophiles to the plate surface without complex coupling chemistry. The structure of the matrix, which has a thick-ness of up to 50 nm, also reduces unspecific binding to a minimum. 
The three-dimensional epoxy 96 well microplates are used mainly if adsorptive binding of peptides or oligonucleotides, for example, to high/medium binding surfaces is ineffective or the binding strength is not sufficient. Areas of application include detection methods such as ELISA, ELI-Spot, protein and peptide arrays and DNA binding. 
The 3D epoxy surface is chemically and mechanically highly robust and features particularly homoge-neous surface functionalisation. The microplates with a 3D epoxy surface are free of detectable DNases and RNases. The shelf life at room temperature is two years.