AMSBIO has announced the introduction of new aptamer kits for cell isolation and flow cytometry.
Aptamers are oligonucleotides or peptides that bind to a specific target molecule. Aptamers are useful in biotechnological and therapeutic applications as they offer molecular recognition properties that rival that of the commonly used biomolecule, antibodies. In addition to their discriminate recognition, aptamers offer advantages over antibodies as they can be engineered completely in a test tube, are readily produced by chemical synthesis, possess desirable storage properties, and elicit little or no immunogenicity in therapeutic applications.
The AptoPrep™ cell isolation kit products from AMSBIO combine the advantage of the specificity of aptamer to target cell with the convenience of isolation/elution of a particular cell from complex cell samples. The new kits offer unique characteristics and provide advantages over alternative methods. AptoPrep™ cell isolation kits deliver positive isolation in as little as 30 min. Mild and unique cell releasing technology allows you to isolate bead- and aptamer-free cells in as little as 1 hour. Incorporating bifunctional aptamer labeled with FITC and biotin the kits allow you to perform cell isolation and flow cytometry analyses simultaneously, further improving your productivity. Supplied as a complete kit (biotinylated aptamer, streptavidin magnetic bead, and buffers) - AptoPrep™ cell isolation products deliver unmatched convenience, increased consistency and reliability.
AMSBIO has also introduced a new range of dye-conjugated monoclonal aptamers specifically designed to monitor protein expression by flow cytometry with high specificity by minimising the background caused by non-specific binding. Manufactured to ensure no batch-to-batch variation and compatible with all flow cytometers - AptoCyto™ flow cytometry aptamers facilitate quantitative, multi-parameter analysis of cell populations based on the expression of cell surface and/or intracellular molecules. Based upon fluorescent dye-conjugated aptamers - AptoCyto™ flow cytometry kits are stable for at least several months at room temperature.