The University of Colorado and Malvern Instruments: Joining forces to help make safer biopharmaceutical products

John Carpenter is a Professor of Pharmaceutical Sciences in the Department of Pharmaceutical Sciences at the University of Colorado, Anschutz Medical Campus. His laboratory is involved in researching the causes and control of aggregates and particles in therapeutic protein products which occur during manufacturing, shipping, storage and delivery to patients.  This research is important as it contributes to improvements in product quality and therefore to reductions in adverse reactions of patients to aggregates and particles within biopharmaceutical products, which can include immune responses and dangerous infusion reactions. Also, by investigating the roles of key biophysical properties in protein stability and degradation, rapid and rational formulation strategies can be developed to help ensure that a product’s stability is properly optimized.

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