A unique opportunity to learn from and to interact with key opinion leaders and experts in the fields of biophysical analysis and particle characterization. A not to be missed agenda featuring case study presentations, panel discussions and solution-specific breakout sessions. Explore the key elements of protein stability through rational approaches and concerted use of biophysical technologies.
This event is free to attend.
8:30- 9:00 Registration
9:00-9:10 Welcome address
9:10-9:45 Keynote presentation. John Carpenter. Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado Denver. Aggregates and particles in therapeutic protein products: Causes, characterization and control
9:45-10:15 Amber Fradkin, Director, Particle Characterization Core Facility, KBI Biopharma. Critical methods for counting and sizing subvisible particles.
10:15-10:45 Jennifer McManus, Head of Chemistry Department, Maynooth University. The chemical and physical basis for protein self-assembly.
10:45-11:20 Coffee break (Plus Poster Session)
11:20-11:50 Chris Vessely. Senior Consultant Analytical and Formulation Development, Biologics Consulting. Beyond the release panel in support of comparability studies and regulatory filings.
11:50 -12:20 Panel discussion with speakers
12:20:13:10 Networking lunch
13:10-16:00 Breakout sessions.
13:10-13:40 Protein conformational stability beyond Tm. Led by Natalia Markova, Malvern Panalytical.
13:40-14:10 Multi-parametric characterization of proteins with multiple-detection SEC. Led by John Stenson. Malvern Panalytical
14:10-14:40 Extended characterization of particles. Led by Amber Fradkin, KBI Biopharma and Debbie Huck-Jones, Malvern Panalytical
14:40-15:00 Coffee break (Plus Poster Session)
15:00-15:30 Best practices of counting and sizing subvisible particles with Resonant Mass Measurements. Led by Judy Hadley. Malvern Panalytical
15:30-16:00 Protein characterization with DLS. Led by Patrick King. Malvern Panalytical
Who should attend?
The workshops is directed to scientists, lab heads and department managers in industry, CRO/CDMO sector and academia.
For travel and accommodation recommendations please contact email@example.com
What will you learn?
• protein characterization
• candidate selection
• formulation development
• stability profiling
• analysis of aggregation content and extended particle characterization
• biosimilarity and comparability analysis.