Performance

• Very high resolving power—up to 240,000 FWHM—facilitates analysis of low-abundance components in complex samples and resolves isobaric species and isotope fine structures with confidence
• Ion optics with novel neutral-blocking technology and an advanced detection system increase system robustness and quantification capabilities
• Advanced signal processing combined with fast scanning ensures UHPLC compatibility
• Multiple fragmentation techniques—CID, HCD and optionally ETD—provide versatility and complementary data
• Innovative pre-amplifier electronics improve sensitivity
• Parallel MS and MSn capability speeds analyses

Comprehensive Proteomics Analyses

• Very high resolution and complementary fragmentation modes facilitate top-down protein identification and characterization
• ETD option preserves labile side chains while fragmenting the peptide backbone for improved analysis of PTMs
• Fast scanning combined with high resolution and high spectral quality yields more protein identifications in a single analysis
• Very high resolution and selectivity in both full-scan MS and MSn modes enhance relative quantification results from stable isotope labeling or isobaric mass tagging experiments

Productive Metabolism and Metabolomics Research

• Very high resolution distinguishes components in complex matrices
• Sensitivity ensures detection of more metabolites
• High-quality MSn spectral trees provide extensive structural information for metabolite identification and the location of modification sites
• Improved robustness lowers maintenance, enabling 24/7 operation when running complex biological matrices

Application-Specific Software

• Thermo Scientific™ Mass Frontier™, MetWorks™, ProSightPC, ProteinCenter™, Proteome Discoverer™ and SIEVE™ software as well as PEAKS™ software are all available to increase productivity for specific tasks or applications.