The Sysmex XE-5000 Automated Hematology System utilizes the power of fluorescent flow cytometry and hydrodynamic focusing technologies. Using a unique and advanced diode laser bench, Sysmex fluorescent flow cytometry provides the sensitivity needed for measuring and differentiating cell types in whole blood and body fluid samples. Fluorescent technology and hydrodynamic focusing enable the XE-5000 to consistently differentiate normal WBC, RBC and PLT populations from abnormal populations, thereby decreasing the number of manual interventions. The XE-5000 technology provides clinically relevant and reportable parameters. 

• Fluorescent NRBC count with excellent sensitivity and specificity to lower review rates 
• Provides improved low end sensitivity 
• Enables rapid reporting 
• Provides efficient automated correction of WBC and differential results 
• Immature granulocyte count (IG% and #) offers reportable, quantitative results for metamyelocytes, myelocytes and promyelocytes 
• Reduce false positive and false negative rates 
• Obtain result consistency by reducing tech-to-tech variation in reporting manual differentials 
• Improve turnaround time with fewer manual differentials  
• Platelet counts by a fluorescent optical method and by traditional impedance technology to improve accuracy of very low and very high PLT counts 
• Obtain accurate counts when interferences are present 
• Offers automated judgment for reporting PLT-O or PLT-I through instrument settings 
• Retic: Fluorescent reticulocyte count to reduce manual confirmation methods and their inherent errors 
• Eliminate common interferences to avoid manual counts 
• RET-He: Reticulocyte Hemoglobin content measures the incorporation of iron into the red cell to assist the physician with anemia evaluation and management (e.g., functional iron deficiency anemia) 
• Provides rapid and direct analysis of an earlier stage of RBC development 
• Is an established parameter used in KDOQI (Kidney Disease Outcome Quality Initiative) guidelines for assessing the initial iron status of patients 
• Supports effective monitoring of costly drug protocols for cell stimulation 
• IPF: Immature platelet fraction to help the physician monitor thrombopoietic activity of the bone marrow 
• Ensures accuracy and sensitivity in measurement of immature platelets 
• Offers delineation of abnormal platelet populations seen by physicians in disease states such as AITP (autoimmune thrombocytopenic purpura) or TTP (thrombotic thrombocytopenic purpura) 
• Enables rapid reporting of results for prompt clinical information 
• HPC: Quantitative Hematopoietic Progenitor Cell count as a screen that can be used by the physicians to determine the presence of hematopoietic progenitor cells in peripheral blood and cord blood samples 
• Offers quality information to better assist physicians with patient treatment protocols 
• Allows rapid analysis versus conventional methods for prompt determination of optimal stem cell harvest time 
• Reduces costs as the system does not require additional reagents, sample volume or specific technical expertise 
• Body Fluids: Excellent low end sensitivity with seven parameters, including a 2-part Differential 
• Provides expanded sensitivity and linearity: WBC and RBC counts reportable to three decimal places 
• Eliminates the need for manual counts by providing a 2-part Differential 
• Performs an automated background check prior to analyzing samples