SCIEX - TripleTOF 4600
The TripleTOF 4600 System makes routine high-resolution, accurate-mass MS and MS/MS available to any laboratory. Bu...
The TripleTOF 4600 System makes routine high-resolution, accurate-mass MS and MS/MS available to any laboratory. Built on the innovative breakthrough in LC/MS/MS performance of the original TripleTOF 5600, it uniquely integrates comprehensive, qualitative exploration, rapid profiling, and high-resolution quantitation workflows on a single platform. The TripleTOF 4600 combines highest-sensitivity detection in its class, high resolution with at least three-fold better acquisition speed, and stable mass accuracy over days of acquisition.
- High resolution at unparalleled speed with 10 msec accumulation time
- Highest sensitivity in class – lowest limits of quantitation (LOQ) for a high-resolution system and equivalent to high-performance triple quadrupoles
- SmartSpeed™ 100Hz Acquisition delivering high-resolution for high-speed chromatography – up to 100 spectra in a second or 50 spectra in a second while maintaining intelligent real-time data filtering (Information-Dependent Acquisition, IDA)
- EasyMass™ Accuracy without continuous recalibration – over 50 hours of continuous LC/MS operation provides less than 2 pmm RMS
- High throughput – compatible with the MPX™-2 High Throughput System to increase laboratories throughput up to two-fold by multiplexing two LC streams in a single mass spectrometer
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Features of TripleTOF 4600
High-Sensitivity with QJet® Ion Guide and Accelerator TOF™ Analyzer
Low-abundance analytes easily discovered, identified, and quantified.
SmartSpeed 100Hz Acquisition
The fastest high-resolution system that generates more high-quality information from every sample even when using fast chromatography.
EasyMass Accuracy
Achieves high mass-accuracy without continuous recalibration, making it the easiest-to-use system for routine accurate mass.
One Touch Productivity Software
Increases productivity by facilitating powerful workflows to create information out of data
Explore Workflow
Explore complex samples in greater depth: Select up to 50 precursors per second – and generate high resolution and high mass-accuracy MS/MS data using powerful IDA (Information-Dependent Acquisition) algorithms and high-resolution, accurate-mass MS and MS/MS.
Profile Workflow
Profile samples for quant and qual in a single run: Quantify virtually every compound in the sample with high-resolution MS quantification and fast chromatography; confirm compound identity with high-resolution, accurate-mass MS/MS; and then mine the data for the information you need
Quantify Workflow
Quantify analytes with high-resolution MRM transitions for highest specificity and confidence: Obtain high-resolution at high and low masses in the same spectrum for high-resolution, MRM-like quantification. The LOQs and dynamic range are equivalent to high-performance triple quadrupoles. Cycle times are as low as 10 msec and generate superior peak definition, even with fast LC separations. Quantification requires little optimization, and you can choose multiple fragments per precursor from the acquired full-scan MS/MS data.
General Specifications
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