Spark Holland's easy introduction to on-line SPE. The Symbiosis™ Fixed SPE system can be connected to any LC, UHPLC and LC-MS configuration. The system works with the Spark 10 mm SPE cartridges or with a third party SPE column. Spark introduces two versions; the "Routine" Fixed SPE with one Spark cartridge or one SPE column and the Advanced" Fixed SPE 6 cartridges or SPE columns and the possiblity to bypass the SPE module and perform a direct LC injection.