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CEM Corporation - Liberty Blue™

Manufactured by  CEM Corporation
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Peptide Synthesis Made Fast and Efficient

CEM Corporation is transforming the way chemists perform peptide synthesis once again with the introduction of the Liberty Blue microwave peptide synthesizer. More than just a facelift, the Liberty Blue system has been designed for maximized speed and efficiency. With 4 minute cycle times and a 90% solvent reduction, no other peptide synthesizer on the market can even come close to the performance of the Liberty Blue. Couple with that unparalleled peptide quality along with greater flexibility and improved reliability, Liberty Blue is the system of choice for all your peptide synthesis needs.   
   
The Liberty Blue system's combination of microwave peptide synthesis along with rapid liquid handling offers several advantages over conventional synthesis conditions including:   
       
  1. Shorter reactions resulting in only 4 minute cycle times   
  2. Higher purity peptides than conventional synthesis   
  3. Use of standard, inexpensive peptide synthesis reagents   
  4. Synthesis of peptides impossible to synthesize under conventional conditions   
  5. License included allowing the use of microwave energy for both the coupling and deprotection steps   
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Features of Liberty Blue™

Remarkably Fast   

  • 4 minute cycle time   
  • Rapid reagent addition   
  • Optimized synthesis methods   
  • >80% time reduction compared to 1st generation microwave synthesizers   
  • Difficult peptides such as A-beta in hours rather than days   

Maximum Efficiency   

  • Up to 90% solvent reduction   
  • Less reagent usage   
  • No priming required   
  • Judicious use of solvent for washing   
  • Accurate and precise reagent addition   

Benefits of Microwave Control   

  • Only system capable to using microwave energy for both the coupling and deprotection steps   
  • Complete control over power, temperature and time for each step   
  • Rapidly change temperature from one stage to the next   
  • Easily synthesize peptides with temperature sensitive amino acids without unwanted side reactions   

Peptide Sequence: GEQKLGAib*AibASEEDLG-NH2

General Specifications
Depth 18 in
Height30 in
Width 20 in
Power Requirements 120V/60Hz or 240V/50Hz
Additional Specifications

Synthesis Scale:  
0.020 – 5 mmol   
Reaction Vessel Sizes: 
10, 30, and 125 mL standard   
Chemistry: 
Fmoc only   
Activation Method: 
In situ, standard activators   
Amino Acid Reagents: 
20 plus 7 additional positions   
External Bottle Positions: 
2 plus 7 additional positions   
Temperature Measurement: 
In situ Fiber-optic   
Fluid Measurement: 
Flex-Add - amino acids, activator, activator base.  
Timed delivery – main wash, deprotection   
Agitation: 
Programmable inert gas bubbling   
Waste Container: 
1 L reservoir with overflow detection   
Controller  
Laptop with wireless option standard   
Reports:  
Printable .pdf file for each method created. Log created during each run of every step performed   
License: 
The purchase of this instrument includes a grant of a limited, non-transferrable license to use this instrument for microwave peptide synthesis using microwave energy for both the coupling and deprotection steps.   
Patents:  
US7393920; US7582728; US8058393; EP1491552; JP4773695, with additional worldwide patents pending

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