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CEM Corporation - Liberty XL™

Manufactured by  CEM Corporation
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The Liberty XL is a mid-scale microwave peptide synthesizer capable

Developer of the first microwave peptide synthesis system, CEM is the leader in the field and we continue to expand the scope of this technology to provide systems to satisfy the needs of all peptide chemists. The Liberty XL is a mid-scale microwave peptide synthesizer capable of preparing hundreds of grams of peptide in an automated fashion with all the speed and efficiency of microwave technology. Using the Liberty XL, chemists can now quickly generate enough peptide material to fulfill further testing or for a pre-clinical trial in high purity and yield.
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Features of Liberty XL™

The Microwave Advantage   

  • License included with each system allowing the use of microwave energy for both the coupling and deprotection steps   
  • Fastest cycle times available Unparalleled peptide purity and yield compared to conventional synthesis   
  • No concern for thermal run-away with instant on/off power control   
  • Access to peptides impossible to synthesize under conventional conditions   

Flexibility   

  • 2.5 L reaction vessel providing a synthesis scale range up to 100 mmol   
  • 20 amino acid positions with either aliquot or full volume delivery   
  • Fully automated operation or semi-automated for critical synthesis steps   
  • Easily transfer methods from Liberty Blue system   
  • Simple vessel design makes resin transfer and clean up easy   

Speed and Efficiency   

  • Cycle time of less than 30 minutes   
  • Direct and accurate temperature control with fiber optic probe   
  • Inert atmosphere for reagents and reaction vessel   
  • Efficient washing and agitation
General Specifications
Depth 29 in
Height64 in
Width 48 in
Power Requirements 200/208/230 VAC (200-253 VAC), 60 Hz, 15A @ 230 VAC 220/240 VAC (202-250 VAC), 50 Hz, 15A @ 240 VAC
Additional Specifications

Synthesis Scale:  
10 – 100 mmol   
Reaction Vessel Sizes: 
2.5 L   
Chemistry: 
Fmoc only   
Activation Method: 
In situ or pre-activation, standard activators   
Amino Acid Reagents: 
20 (1 L capacity)   
External Bottle Positions: 
4   
Temperature Measurement: 
In situ Fiber-optic   
Fluid Measurement: 
Timed delivery    
One shot option   
Fluid Transfer: 
Positive nitrogen pressure for amino acids   
Independent pumps for each external position and RV drain   
Agitation 
Mechanical   
Waste Container: 
Variable reservoir with overflow detection   
Controller: 
User selectable desktop or laptop with wireless option standard   
Reports: 
Printable .pdf file for each method created. Log created during each run of every step performed   
License: 
The purchase of this instrument includes a grant of a limited, non- transferrable license to use this instrument for microwave peptide synthesis using microwave energy for both the coupling and deprotection steps.   
Patents: 
US7393920; US7582728; US8058393; EP1491552; JP4773695, with additional worldwide patents pending

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