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Malvern Panalytical - Zetasizer APS

Manufactured by  Malvern Panalytical
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The highest accuracy automated protein size measurement

The Zetasizer APS transfers 20µL sample from each well to a precision quartz flow cell for measurement. The cell environment is optimized for precision temperature control and optical clarity to ensure the most accurate and precise results. This means that any industry standard disposable or reusable plate can be used without concern for transparency or scratches on the plate that would affect the result.
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Features of Zetasizer APS

The Zetasizer APS enables you to:

  • Investigate your protein over a large number of environmental conditions with minimal user intervention.
  • Determine whether a protein is well-behaved in a buffer or whether aggregates are present.
  • Assess purity to screen for suitable crystallization buffers.
  • Measure aggregation temperature (melting point) to predict or compare stability.
  • Uses industry standard 96 or 384 well plates.
  • Measures size, size distribution, aggregation temperature.
  • Use multiple measurement protocols on a single plate.
  • Graphical plate scheduler to simplify set up.
  • Color coded results graphic to aid data interpretation.
  • Complete plate method stored for subsequent plates.
  • Plate sampling technology ensures highest result accuracy.
  • 2 - 90°C temperature range for measurement.
  • 4 - 40°C temperature range for protein storage.
General Specifications
Depth 410 mm
Height420 mm
Width 500 mm
Power Requirements 100VA
Weight22.5 kg
Light SourceLaser 830nm, Max 60mW
Additional Specifications

Measurement type 1 Particle size and molecular size

Measurement range: 0.3nm – 2.0 microns* (diameter)

Measurement principle: Dynamic Light Scattering

Minimum sample volume: 20µL

Accuracy: Better than +/-2% on NIST traceable latex standards

Precision/Repeatability: Better than +/-2% on NIST traceable latex standards

Sensitivity: 0.1mg/mL 15kDa protein (Lysozyme)

Measurement type 2 Aggregation temperature (melting point)

Measurement range: 2ºC - 90°C +/- 0.1.**

Measurement principle: Dynamic light scattering

Minimum sample volume: 20µL

Temperature control range: 2ºC - 90ºC +/- 0.1.**

Compatible plate types: 96, 384 well (SBS standard) †

Light source: Laser 830nm, max 60mW

Laser safety: Class 1

Operating environment:

  • Temperature: 15°C – 30°C
  • Humidity: 35% - 80% non-condensing

Recommended computer specification: Intel i5 processor PC, 4GByte RAM, 500GByte hard disk drive, 1280 x 800 screen resolution (widescreen), or 1280 x 960 (4:3), CD-ROM drive, USB port

Operating platforms: Windows XP, Windows 7, compatible with both 32bit and 64bit operating systems

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