The DIOSNA Compact Granulation System CGS combines the process steps mixing, granulating and drying in one compact granulation unit. It provides accelerated product transfer and reduced GMP space requirements.     
     
Wet granulation of pharmaceutical tablet mixtures with subsequent fluid bed drying is a basic step in the production of solid dosage forms. The CGS concept provides optimal integration of the process steps of mixing, granulating and drying. The outlet of the mixer-granulator is directly linked to the inlet of the fluid bed dryer, eliminating long transfer pipes. Thus product contact surfaces are minimized and the yield is increased. Even sticky granules which are difficult to transport by pneumatic conveying can be transferred easily and quickly into the dryer.     
     
Installation expenditure for the CGS is low. Mixer and dryer are supported by one common frame which makes additional framework unnecessary. The operating media are supplied through-the-wall from the technical zone.     
     
Due to the compact installation, the floor space required by the CGS plant is very small. 
     
All connection lines of the CGS from feeding the mixer to discharging the dryer are integrated into the automatic cleaning system.