Supelco/Sigma-Aldrich - Supelclean EZ-POP NP SPE Cartridges

Manufactured by  Supelco/Sigma-Aldrich
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Simple, Effective Extraction of Lipophilic Persistant Organic Pollutants from Oily Samples

This multi-bed solid phase extraction (SPE) cartridge offers superior cleanup for the extraction of non-polar persistent organic pollutants (POPs), specifically heavy and light polynuclear aromatic hydrocarbons (PAHs), from edible oil matrices such as olive and corn oil.

This dual layer SPE cartridge contains both LC-Florisil® (upper layer) and Z-Sep/C18 (lower layer) sorbents, separated by a polyethylene frit. Fatty matrix is preferentially retained by the cartridge while non-polar POPs, such as PAHs, are washed through using acetonitrile. The resulting extract is suitable for either GC-MS or HPLC-FLD analysis.

The top Florisil layer is a polar adsorption media that interacts with polar functional groups such as acids and alcohols. The bottom Z-Sep/C18 layer is comprised of a mixture of Discovery® C18 and Z-Sep sorbents. Z-Sep/C18 binds fatty matrix through hydrophobic interaction as well as Lewis acid-base interactions. -

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Features of Supelclean EZ-POP NP SPE Cartridges
  • Removes both fatty matrix and polar interferences from oil matrices for the analysis of a full range of PAHs (2-6 rings) and non-polar POPs
  • Produces cleaner extracts and gives better overall recoveries than other SPE methods
  • Easier and more versatile methodology than other SPE methods, requiring fewer steps and little to no method development work
  • Produces final extracts in GC and HPLC compatible solvent
General Specifications

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Additional Specifications


  • bed A, 1.25 g (Supelclean™ LC-Florisil®)
  • bed b, 1.25 g (Z-Sep/C18)

Packaging: pkg of 20

Volume: 12 mL

Retention Mechanisms: Lipid matrix is retained via normal phase, hydrophobic, and Lewis acid-Lewis base interactions

Sample Matrix Compatibility: Oils

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