AMSbio - mRNA-In™ Neuro Transfection Reagent

Manufactured by  AMSbio
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mRNA-In™ Neuro, is a new, mRNA transfection reagent specifically designed and optimized for high efficiency mRNA...

mRNA-In™ Neuro, is a new, mRNA transfection reagent specifically designed and optimized for high efficiency mRNA delivery with exceptionally low cytotoxicity in neurons. Unlike other competitor reagents, mRNA-In™ Neuro requires very low amounts of RNA to achieve maximum delivery while maintaining optimal cell viability. 
 
mRNA-In™ Neuro Transfection Reagent is a next generation low-toxicity mRNA delivery system for achieving maximum transfection efficiency in hard to transfection neurons. It is well suited for various neurobiology applications, including neurotoxicity and neurite outgrowth development. Data here shows mRNA-In™ typically achieves 70% or greater transfection efficiency in primary neurons. With mRNA-In™ Neuro, mRNA expression levels using can be adjusted by changing the amount of mRNA transfection. Moreover, mRNA-In™ Neuro requires very low amounts of mRNA (up to 5-fold less that competitor reagents) to achieve maximum transfection efficiency in neurons, significantly minimizing unintended off-target immune activation and toxicity effects.
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Features of mRNA-In™ Neuro Transfection Reagent

Maximum efficiency with low amounts of mRNA - Maximally effective with very low amounts of mRNA, significantly minimizing potential adverse off-target cytotoxic effects and supporting maximum cell health and viability. 

High expression, low toxicity - Achieves high mRNA efficiency and protein expression in hard to transfect neurons while maintaining optimal cell health for uncompromised post-transfection assay results. 

Versatile performance - Highly efficient and reproducible transfection performance across a wide range of primary cells. 

Rapid expression and Easy to Use - Use without the risk of integration with the cellular host genome and observe more rapid expression as early as 4 hours post-transfection. 

Well suited for various applications - Shown to be effective across a range of applications, including neurotoxicity and neurite development.

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