For the isocratic UPLC analysis of analytes without a UV chromophore, the ACQUITY Refractive Index Detector offers unparalleled performance. The low-dispersion fluidics were designed to match the performance needed for narrow UPLC peaks while still delivering stable baseline performance, low noise, and a wide, linear dynamic range.      
     
Refractive index detection is one of the key enabling technologies in the ACQUITY Advanced Polymer Chromatography System. The low-dispersion characteristics of the ACQUITY RI Detector are critical for maintaining the high-resolution molecular weight separations achieved on the ACQUITY APC columns, delivering unprecedented characterization of low molecular weight polymers and their oligomers.     
     
HPLC/RI applications, including sugars, alcohols, saccharides, and pharmaceutical QC, can easily be transferred to UPLC system technologies to enable improved resolution and reduced analysis times.