Easy and simple   

• Significantly increased speed of sample processing   * 3-step sample preparation   * Easily automate entire protocol for high-throughput processing   

  Reliable results       * Increased reproducibility over existing protocols   * Higher sensitivity    * Higher data confidence   

  Significantly reduces sample preparation time    

  Typically it takes less than 60 minutes (dependant on sample complexity) to achieve full digestion, whereas an in-solution digest can take up to 24 hours.    

  Higher sequence coverage   

  Higher sequence coverage is due to the removal of the reduction and alkylation steps and absence of trypsin. This reduces the number of chemicals and presence of trypsin in the final sample, as well as fewer post translational modifications, resulting in lower suppression of signal during LC-MS analysis.