SCIEX - PA 800 Plus Pharmaceutical Analysis System
Manufactured by SCIEX
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For research use only. Not for use in diagnostic procedures.
Therapeutic proteins make up a rapidly growing segment of global pharmaceutical production. These complex molecules require accurate characterization of product purity, heterogeneity, and identity. This includes data regarding their stability, shelf life and related manufacturing processes.
Automated and Quantitative Analysis of Biologics
The PA 800 Plus Pharmaceutical Analysis System* was designed in collaboration with biopharmaceutical development and QC groups. This platform provides analysts with robust and easy-to-use characterization, integrating quantitative, qualitative and automated solutions for protein purity, charge isoform distribution and glycan analysis. During the design of the PA 800 Plus, we emphasized assay portability, enhancing the overall system utility in multi-user, multi-instrument facilities.
Automated and Quantitative Analysis of Biologics
The PA 800 Plus Pharmaceutical Analysis System* was designed in collaboration with biopharmaceutical development and QC groups. This platform provides analysts with robust and easy-to-use characterization, integrating quantitative, qualitative and automated solutions for protein purity, charge isoform distribution and glycan analysis. During the design of the PA 800 Plus, we emphasized assay portability, enhancing the overall system utility in multi-user, multi-instrument facilities.
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Features of PA 800 Plus Pharmaceutical Analysis System
Automated applications provide reproducible and quantitative results:
High resolution SDS-gel separation for protein purity determination
Automated, Quantitative IgG Purity Analysis
Advanced capillary Isoelectric Focusing (cIEF) for charge heterogeneity analysis
Carbohydrate profiling for assessment of glycoprotein microheterogeneity
Simplified operations and a robust platform enhance operational efficiency:
Specialized software quickly guides routine users from set-up through results
Innovations in system design ensure dependable operation and durability, with minimal maintenance
Modular UV, photodiode array and laser-induced fluorescence detectors can be easily interchanged
The PA 800 Plus Pharmaceutical Analysis System provides a comprehensive, automated, and quantitative solution for the characterization and analysis of proteins. Innovative system design ensures dependable operation and durability. The PA 800 Plus application menu includes SDS-gel molecular weight analysis, charge heterogeneity analysis utilizing advanced capillary isoelectric focusing technology, and carbohydrate profiling for the assessment of glycoprotein microheterogeneity. Modular design provides for the simple interchange of detectors.
The PA 800 Plus System includes:
High-resolution Separation Module
High-sensitivity UV, PDA, and Solid-state Laser-induced Fluorescence Detection
Sample Storage Temperature Control
High-speed System Controller with 32 Karat™ Version 9.0 and PA 800plus software
Validated Applications for SDS-MW, IgG, cIEF, and Glycan Analysis
Starter Kit Containing Necessary Hardware Supplies to Operate the System
Installation Qualification and Operation Qualification of the System
System Application Installation and Training
The PA 800 Plus Pharmaceutical Analysis system, the PA 800 Plus provides an automated and quantitative solution for the analysis of protein purity and molecular weight utilizing SDS-gel capillary electrophoresis. The innovative system design ensures dependable operation and durability. Additional detectors are available for future upgrades.
General Specifications
| Depth | 28.4 in |
| Height | 29.2 in |
| Width | 25 in |
| Power Requirements | 100-240 VAC, 50-60Hz |
| Weight | 188 lbs |
| Electropheresis Type | Capillary |