The USP has suggested that physical and (MQ) mechanical attributes (such as height, centering, wobble, and speed) of the Dissolution Instrument be measured. Followed by a chemical calibration / verification using Prednisone Tablets (PVT). 

The US Food and Drug Administration has decreed that a mechanical qualification (ASTM E2503) can be used to validate apparatus 1 and 2. Once a unit meets all of the mechanical specifications included in the MQ, it is considered calibrated. 

Validation Tools by Distek support both techniques. All tools arrive ready-to-use with National Institute of Standards and Technology (NIST) traceable calibration certificates as well as ASTM E2503 and USP Toolkit enhanced mechanical calibration.