Developing immunoassays to monitor HCP impurities faces many challenges. Typically, hundreds of different HCPs are produced during cell culture. HCP impurities may vary in abundance, physicochemical and immunogenic properties, and contribute differently to the overall response of the assay. A single, generic assay for HCP cannot cover the diversity of HCP mixtures from different bioprocesses. Therefore, reliance on one kit risks missing HCPs that could lead to adverse effects. 
 
Gyros has therefore developed a panel of Gyrolab CHO-HCP kits to complement Gyrolab CHO-HCP Kit 1 and increase the possibility of finding a kit that best matches your bioprocess. 
 
Gyrolab CHO-HCP Kits 2–5 provide diversity through being generated in both goat and rabbit using slightly different antigens. They have been optimized for the Gyrolab platforms to provide consistent and sensitive assay performance without the need for assay development. The analytical performance of Gyrolab CHO-HCP Kits 2 -5 is similar to Gyrolab CHO-HCP Kit 1.