inSphero - 3D InSight™ Multi-donor Human Liver Microtissues
Manufactured by inSphero
3D InSight™ Multi-donor Human Liver Microtissues offer structural and functional robustness of our single-donor microtissues.
3D InSight™ Multi-donor Human Liver Microtissues offer the same structural and functional robustness of our single-donor microtissues, but offer a more diverse genetic background to help mitigate potential bias in a single-donor microtissue originating from CYP polymorphisms. By pooling hepatocytes from 5 male and 5 female donors, multi-donor microtissues more closely approximate the average human response, and extend donor lot availability to ensure a long-term supply of donor material. Available as co-cultures with Kupffer cells, or as hepatocyte monocultures, multi-donor microtissues are ideal for in vitro DILI detection and prediction, compound toxicity screening, mechanistic tox studies, and DMPK.
Active Questions & AnswersAsk a Question
There are no current Discussions
Need Equipment Support?
Documents & Manuals
There are no Documents or Manuals available.
Features of 3D InSight™ Multi-donor Human Liver Microtissues
- Pool of 10 individual donors better reflects average response of a population * Co-culture with Kupffer cells for highest biological relevance * Organotypic, functional liver model suited for testing over extended time period
General Specifications
There are no General Specifications available.