ibidi - Fuse-It-mRNA
Manufactured by ibidi
A fusion reagent used to rapidly transfer mRNA into the cytoplasm of living cells Immediate mRNA trans...
A fusion reagent used to rapidly transfer mRNA into the cytoplasm of living cells
- Immediate mRNA translation - protein synthesis detectable after 15-30 minutes
- Highly efficient, especially in primary cells (e.g., neurons or HUVECs) and stem cells
- Fastest mRNA delivery - no endocytosis or lysosomal degradation; no gene transfer into the nucleus needed
- Extremely low cytotoxicity
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Features of Fuse-It-mRNA
Applications
mRNA translation and degradation studies
Protein biochemistry studies: synthesis, folding, processing, stability, localization, degradation
mRNA transfer into primary cells without generating genetically modified organisms (GMO)
Genome engineering by RNA-only CRISPR/Cas technology
Technical Features
Transfection-independent transfer of mRNA into living cells
mRNA transfer completed within 15 - 30 minutes
No endocytosis involved
No lysosomal degradation needed
No gene transfer to the nucleus
Protocol optimized for the transfer of functionally capped and polyadenylated mRNA
No Biosafety Laboratory Level 1 or 2 necessary
Excellent biocompatibility with low cytotoxicity
General Specifications
There are no General Specifications available.