Waters - UniSpray Ion Source

Manufactured by  Waters
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A novel ion source for ionization of a broader range of compounds

The UniSpray™ ion source allows you to see more of your sample within a single analysis when compared to ESI, APCI or APPI. This enables UniSpray to offer: 
  1. Greater ionization efficiency - A broader range of compounds ionized in a single run and potential for increased sensitivity 
  2. Reduce the need to change ionization source between different analyses 
  3. Tool free routine maintenance - capillary and target pin replacement 
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Features of UniSpray Ion Source

Expanding the breadth of ionization  The unique geometry of the UniSpray ion source generates several different mechanisms to produce smaller droplets and enhance desolvation. These effects combine together to generate a greater number of free ions from the same amount of sample when compared to traditional ionization modes such as electrospray and typically results in an increase in response across a wide range of compounds. 

The combination of a broader range of analytes and a potential boost in response give the possibility to consolidate several analysis methods into one, or even just remove the need to change over sources between analyses, saving you time and increasing your laboratory efficiency. 

Robust, reproducible and easy to use  The single piece probe design and bespoke probe adjuster on the UniSpray ion source allow for simple optimization and tool free routine maintenance of the UniSpray source, ensuring you get the same results, no matter who operates and maintains your instrumentation. In a study of 1000 injections of protein precipitated plasma, analyzing for caffeine, <3% RSD was observed across the entire series of injections. 

Compatible with the latest TQ Mass Spectrometer for challenging compounds  The UniSpray ion source is compatible with the Xevo TQ-XS, Waters' most sensitive mass spectrometer. The Xevo TQ-XS incorporates the StepWave XS™ ion guide which provides increased sensitivity for challenging compounds, and an enhanced detection system with six orders of linear dynamic range to ensure that sensitivity is accessible. Combined with the Xevo TQ-XS, the UniSpray ion source expands the scope of ultimate sensitivity analysis allowing a wider range of analytes to be ionized in a single run, delivering results for more compounds than before without having to change sources.

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