Thermo Scientific - Vanquish™ Flex Binary UHPLC System

Manufactured by  Thermo Scientific
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Integrated biocompatible UHPLC system with binary pump

Obtain new benchmarks in accuracy, precision, and sensitivity. The Thermo Scientific™ Vanquish™ Flex Binary UHPLC system is biocompatible with a state-of-the-art binary high-pressure pump and state-of-the-art binary solvent blending. This ultra high performance liquid chromatography system shares all Vanquish values, such as a design focused on uptime, robustness and reliability. Multiple detection options give you the performance you need. Thermo Scientific™ Viper™ Fingertight Fitting connections throughout the system make set up easy. This system is ideal for high-throughput analyses and can be seamlessly coupled to a mass spectrometer (MS).
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Features of Vanquish™ Flex Binary UHPLC System

Drives the Separation with more Flexibility    Extend your capabilities by adding all the flexibility you would expect from leading-edge binary solvent blending. Our SmartFlow pumping technology with automatic compensation for changing eluent compressibility ensures excellent flow and gradient precision, independent of eluent composition and backpressures. This gives you unrivaled retention time precision and highest data confidence. The binary high-pressure mixing results in short analysis time and high sample throughput. The Vanquish Flex Binary system can be seamlessly coupled to Thermo Scientific™ mass spectrometers for unambiguous identification of compounds in complex matrices.   

  • 1000bar (15,000psi) of pump pressure and flow rates up to 8mL/min   
  • Industry-leading flow and gradient precision   
  • 6 solvent channels for binary high-pressure solvent mixing   

Handles the Sample with more Accuracy    Out of the box, Vanquish Flex Split Sampler FT module comes with a vial capacity of 208 samples. Increase to 8832 sample capacity (23 well plates) by adding the optional Vanquish Charger module.   

  • Intelligent sample pre-compression and unsurpassed sample dosage precision   
  • Innovative air stream cooling for maximum sample integrity in both the sampler and the Charger module   
  • Automated workflows with barcode reading   

Controls the Separation with more Confidence    Ensure even temperature throughout using the two thermostatting modes of the Vanquish Column Compartment H module. Avoid performance loss from temperature effects using the system's active pre-heating to ensure solvent entering the column will match the column temperature.   

  • Two thermostatting modes: still air and forced air   
  • Temperature range from 5°C – 120°C   
  • Active pre-heating and post column cooling   
  • Extendable with valve switching options   

Detects the Analyte with more Versatility    Ensure you collect the most information possible from your separation, and benefit from multiple detection options for the Vanquish platform so that no peak remains unseen.   

  • Highly sensitive and linear diode array detection with Thermo Scientific™ LightPipe™ technology   
  • Highly selective and sensitive fluorescence detection   
  • Near universal response for label free detection of non-chromophoric substances with charged aerosol detection   

Driven by Gold-Standard CDS Software    The Vanquish Flex system seamlessly integrates with our award winning Thermo Scientific™ Dionex™ Chromeleon™ Chromatography Data System (CDS) software. Designed with Operational Simplicity™ in mind, Chromeleon CDS software realizes the promise of the Vanquish platform—easier interaction delivering a new UHPLC experience.   

Easy and Reliable Tool-Free Connections    Enjoy tool-free system fluidics setup and other connections thanks to our innovative Viper Fingertight Fittings technology.

General Specifications
Maximum Pressure1000 bar
Flow Accuracy 0.1 %
Additional Specifications

Column Temperature Range   
5°C to 120°C   
Detector Data Collection Rate   
200Hz (including 3D acquisition) under Thermo Scientific™ Dionex™ Chromeleon™ Chromatography Data System 7.2 SR1 control or higher   
Max. Detector Channels   
10 + 3D field   
Sample Temperature Range   
Using Vanquish Charger Module: 4-40°C (22K below ambient at <80% RH)

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