Sigma-Aldrich - BIOshell ™ Fused-Core ® Columns

Manufactured by  Sigma-Aldrich
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Faster Separation of Proteins, Peptides, and Glycans

BIOshell columns are the most recent innovation in Fused-Core particle technology: high efficiency U/HPLC columns for protein, peptide, and glycan separations. BIOshell columns can be operated in HPLC or UHPLC instrumentation equipped with a mass spectrometer or any other  
detector.  
 
The complete BIOshell column lineup includes: 
  • BIOshell A160 Peptide 
  • BIOshell A400 Protein 
  • BIOshell A90 Glycan
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    Features of BIOshell ™ Fused-Core ® Columns

    BIOshell Protein, Peptide and Glycan columns are packed with Fused-Core particles that have been specifically engineered for fast, high-resolution separation of biomolecules. These columns offer a tremendous advantage over conventional column formats by providing increased resolution, faster separations, and lower back pressure. In addition, BIOshell columns offer a level of ruggedness that is not often associated with columns exhibiting such a high level of performance. Some of the benefits realized when using a BIOshell Fused-Core column are as follows: 

    • 40% higher efficiency than fully porous particles of the same size 
    • Heightened bonded phase stability 
    • High temperature stability enabling increased throughput and improved peak shape 
    • Operation at high flow rates 
    • Decreased column pluggage 
    • Compatibility with UHPLC as well as conventional HPLC systems
    General Specifications

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