Improved Peak Shape of Basic Analytes  The CSH C18 column provides exceptional peak shape, particularly for basic compounds under low-pH, weak-ionic-strength mobile-phase conditions.    Improved Loading Capacity  CSH Technology provides exceptional loading capacity, particularly for basic compounds under low-pH, weak-ionic-strength mobile phase conditions. The increased and improved loadability possible with CSH Technology permits the separation, identification and quantitation of closely eluting impurities or degradants.    Selectivity for Methods Development  The CSH Technology fluoro-phenyl and phenyl phases offer the ability to retain polar analytes. Selectivity is manipulated through the use of pH, mobile-phase buffer strength, organic modifier and chromatography column choice.    UPLC to HPLC Method Transfer  The CSH Technology particles used in both ACQUITY UPLC and XBridge HPLC columns differ only in their particle size, enabling seamless methods transfer and the fastest route to an optimized LC method. CSH particles maximize efficiency, improve high-pH stability and improve chromatography column reliability for both UPLC and HPLC systems.