XBridge HPLC and UHPLC columns, utilizing BEH Particle Technology, are built to withstand high pH, high temperatures , and other extreme operating conditions, including volatile eluents, for a wide range of small molecule and biomolecule LC-MS analysis. These columns are available in a broad range of sorbent particles and sizes. XP Columns (2.5 µm) for rapid analytical UHPLC separations, (3.5 and 5 µm) for reliable analytical method development and OBD Prep (5 and 10 µm) for purification chromatography.