The Waters 2465 Electrochemical Detector combines sensitivity, reliability, and simplicity for HPLC electrochemical detection. Its versatile detection modes are ideally suited for analyzing a wide range of compounds. The 2465 Electrochemical Detector’s multiple flow-cell configuration combines working and reference electrode designs to minimize cost and enhance flexibility. The flow cell accommodates several reference electrodes: ISAAC; traditional salt-bridge design, which limits air bubble formation; and Hy-Ref, which is ideal for carbohydrate analysis and is compatible with extreme mobile phases. The detector is designed for ultra-trace analysis and is compatible with both analytical and microbore scale applications.