The rapifleX MALDI PharmaPulse (MPP) accelerates label-free hit finding in drug discovery: rapifleX MPP combines the unambiguousness of mass spectrometry with the required speed to comb through large compound libraries of millions of substances.

The use of mass spectrometry allows the measurement of unmodified substrates in primary screens to avoid false positives or false negatives, making confirmation screens redundant. The system is designed for fully automatic handling of 1536 sample plates to screen more than a million compounds in a week in support of drug discovery.

The MPP system is specifically designed for fully automatic handling 384, 1536, 3072 and 6144 samples per plate, including automated method development and instant export to LIMS.

The new rapifleX MALDI time-of-flight mass spectrometer is the key enabler for the MALDI PharmaPulse solution. It represents a new era in MALDI mass spectrometry. All performance characteristics of the rapifleX MALDI TOF and TOF/TOF instrument surpasses anything seen before.

The new MALDI PharmaPulse 2.0 software solution completes the rapifleX MALDI PharmaPulse mass spectrometer with a tailored software solution for the provision of HTS campaigns – for non-experts in mass spectrometry. This major step enables scientists working in drug discovery to use label-free mass spectrometry for large screening campaigns of millions of substances.