DeNovix Inc. - CellDrop" Automated Cell Counters
Count Cells Without Slides
Count Cells Without Slides
CellDrop™ Automated Cell Counters feature patented DirectPipette™ technology to eliminate plastic slides and cumbersome hemocytometers from routine cell counting. CellDrop Cell Counters feature dual fluorescence and brightfield optics, variable height sample chamber, and powerful, easy-to-use analysis software. The instruments enable the fastest cell counts, viability assessment, and GFP transfection efficiency measurements across the widest range of cell density, cell type and application.
DirectPipette™ Technology
The CellDrop Automated Cell Counter Series brings the familiar Load, Measure & Wipe Clean functionality of microvolume spectrophotometers to cell counting. Traditional plastic slides or glass hemocytometers are replaced by two permanent optical sapphire surfaces. These are positioned parallel to one another by a calibration-free, high-precision mechanism, forming a chamber of precisely defined height. 10µL of cell suspension is pipetted into the chamber, analyzed and simply wiped away with a dry laboratory wipe. The powerful live-view image allows instant verification that cleaning has been successful.
Discover the best practices for the CellDrop Automated Cell Counters here.
Accurate Across the Widest Range of Cell Size and Density
Using conventional counting methods, samples with high or low cell densities require time consuming dilution or concentration steps. The variable height chamber of the CellDrop Automated Cell Counters enables the most accurate counts over the widest cell densities – 7 x 102 – 2.5 x 107 cells/mL. Chamber height can also be adjusted to accommodate almost any cell with a diameter range of 4 to 400µm.
Easy-to-Learn, Powerful-to-Use
Designed by life scientists, the CellDrop EasyApps™ Software exceeds the functionality of high cost cell counters while also delivering the ease-of-use of simpler systems. EasyApps and the high definition, 7″ touchscreen interface provides intuitive cell counting, from sample loading to data exporting in seconds. Pre-installed applications include a range of common applications for one-touch analysis of assays such as Brightfield, Trypan blue, AO/PI, GFP, Yeast, and Nuclei, as well as the ability to create custom methods. CellDrop Cell Counters are a flexible workhorse for the busy, multi-user lab.
- Cell Gating
- Declustering
High Definition cell outlining and declustering algorithms developed by DeNovix provide high accuracy cell counts of regular and irregular cells even at high density
- Primary Cells
- Results
- Exporting
Cell Size Histograms allow easy gating for non-target cells or cell debris. Simply drag the slider to set the cell size of interest.
Flexible reporting options allow easy exporting in a format to suit each lab member. Email results, print to a network printer or save to a USB drive. Results are saved to a built-in solid state drive for extra data security.
21 CFR Part 11 Compliance Ready
EasyApps Secure provides an optional suite of software controls that allow regulated GxP facilities to easily add CellDrop to their cell counting workflow (view the compliance statement). The software is fully integrated within the on-board operating system and includes a range of features essential to ensuring compliance, including:
- Password protected system access
- Integrated electronic signature controls
- Comprehensive user account management
- Secure audit trail recording
- Advanced data handling and export tools
Hazardous Samples?
The small footprint and onboard processing of the CellDrop Cell Counter allow it to fit inside most flow hoods where required. For applications that require the cells to be contained when reading, all instruments also have the ability to read samples in common disposable plastic slides and reusable slides without the need for additional adaptors.
Models
CellDrop is available in Dual Fluorescence and Brightfield (CellDrop FL) or Brightfield (CellDrop BF) models, each with the option of Unlimited Counts or Pay-As-You-Go.
Part Number | Description |
CellDrop FL-UNLTD | 2 Channel Fluorescence Cell Counter with Unlimited Counts |
CellDrop FL-PAYG | 2 Channel Fluorescence Cell Counter- Pay-As-You-Go |
CellDrop BF-UNLTD | Brightfield Cell Counter with Unlimited Counts |
CellDrop BF-PAYG | Brightfield Cell Counter- Pay-As-You-Go |
Patents
US 10,302,568
Japan 6579475
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General Specifications
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Additional Specifications
Dynamic Range | 7 x 102 – 2.5 x 107 cells/ml |
Cell Size Range | 4 – 400 µm |
Sample Volume | 5.0 µL @50 µm chamber height 10 µL @100 µm chamber height (standard) 40 µL @400 µm chamber height |
Measurement Speed | Brightfield- 3 seconds @1 x 10^6 cell/mL Dual Fluorescence- 8.5 seconds @1 x 10^6 cell/mL |
Optical Modes | CellDrop™ FL – Dual Fluorescence, Single Fluorescence, Brightfield, Fluorescence + Brightfield CellDrop BF – Brightfield only |
Sample Surfaces | Optical Sapphire |
Brightfield Illumination | LED 530 nm |
Fluorescence Illumination | LED 470 nm |
Emission Filters | 530 nm +/- 25 nm 645nm +/- 37 nm |
Gesture Recognition | Multipoint touch, swipe, pinch |
Display | 7″ HD Touch Screen |
Glove Compatibility | All common laboratory gloves |
Images | 2048 x 800 px (3.15 MB) with overlay capabilities |
Focus | User-controlled onscreen coarse and fine adjustment |
Detector | CellDrop™ FL – Sony IMX265 CellDrop™ BF – ON Semiconductor MT9P031 |
Connectivity | WiFi, Ethernet, HDMi, USB |
Footprint (LxWxH) | 37 x 21 x 18 cm |
Weight | 8 Kg |
Operating Voltage | 12 VDC |
Approvals | UL/CSA, CE, FCC, Japan CAB |
Manufacturer Location | USA |
Warranty | 2 Years |
Colors | Arctic White |
Internal Storage | 120 GB solid state drive – upgradable to 1 TB |
Accessories | Barcode reader, keyboard, mouse, 20 µL pipette |