Waters - 3100 Mass Detector
The Waters 3100 Mass Detector is a compact, single-quadrupole atmospheric pressure ionization (API) mass detector that...
- Interactive diagnostics software for worry-free system and fluidics optimization and performance checks with IntelliStart™ Technology
- 1 pg sensitivity with either ESI or APCI
- 10,000 Da/sec scan speeds up to 2,000 Da for full compatibility with seconds-wide fast LC peaks
- Simple upkeep and minimal bench space requirements
- Dual orthogonal sampling ionization with ZSpray™ source
- Rapid polarity switching and multi-mode ionization with simultaneous APCI and ESI for comprehensive compound analyses in a single injection, with ESCi® Technology
- Multiple detection strategies available with supported Tunable UV (TUV), Photodiode Array (PDA), and Evaporative Light Scattering (ELS) optical detectors
- Control and data acquisition with Empower™ or MassLynx™ Software
- Optional APPI (Atmospheric Pressure Photo-Ionization) available
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Features of 3100 Mass Detector
- Rapid HPLC separations with shorter columns to maximize sample throughput
- IntelliStart™ Software automates setting up the MS hardware (mass resolution, mass calibration, ion source optimization) and the process of developing compound-specific SIR data acquisition methods
- QuanOptimize™, a sophisticated, optional software package, is available for comprehensive automation of the entire process of quantitation (method setup, data acquisition, data processing, and reporting)
- Robust dual orthogonal API source (ZSpray™): Maximizes source longevity, protects against dirty samples, and allows easy removal and cleaning of source elements without breaking vacuum
- Ionization options include: standard electrospray and multi-mode ionization capability (ESCi®), atmospheric chemical ionization, and dual-mode atmospheric pressure photo-ionization / atmospheric chemical ionization interface
- MassLynx™ MS Software or Empower™ 2 CDS Software solutions suit your analytical requirements
- Optional OpenLynx™ Application Manager provides walk-up access to non-expert users for UPLC/MS applications
- Optional FractionLynx™ Application Manager, as part of an autopurification system. Mass directed autopurification automates sample purification, including the control of fraction collection as well as sample, fraction and data tracking
- Connections INSIGHT® intelligent services provides on-demand, remote diagnostics and online help for your LC/MS system
- Resolves system alerts
- Autotunes and calibrates the system, optimized for your analysis
- Automatically generates SIR methods with ease using integrated fluidics
- Reports on your LC/MS system performance
General Specifications
| Depth | 23.2 in |
| Height | 20.3 in |
| Width | 13.6 in |
| Power Requirements | 230 V, 50/60 Hz, two lines, 3 kW maximum consumption (not including LC equipment) |
| Weight | 110 lbs |
Additional Specifications
Flow Rates:
5-1,000 µL/min (ESI)
200-2,000 µL/min (APCI)
Mass Range: 2-2,000 Da (amu)
Scan Rate: Up to 10,000 amu/sec in continuum or centroid modes
Dynolite Photomultiplier Detector: 8 kV conversion dynode dependent on ion polarity and +9 kV for both modes with the phosphor
Vacuum System: Split flow turbomolecular pump (air cooled)
280 L/sec @ High vacuum connection
205 L/sec @ Interstage Leybold Sogevac SV40 BI Roughing Pump
Integrated IntelliStart Fluidics: Fluidics automation of tuning, calibration, and system QC with IntelliStart control and diagnostics. Two vial positions are prodvided to contain calibrants and samples for tuning which are automatically metered into the mass detector when needed.
Waters Software: MassLynx 4.1 or Empower 2*
Autopurification Software Capabilities:
Solvent monitoring system for solvent and waste reservoirs
Automatic collection time delay calculation
Early run termination
Total flow and gradient calculator
Direct inject
Manual/automated (IntelliStart) instrument optimization, monitoring, tuning, and calibration
Full scan/single ion recording (SIR) data acquisition
Simultaneously, monitoring ESI (±) and APCI (±) with ESCi
Chromatogram/spectrum processing
3D data mapping
Comprehensive quantitation with QuanLynx
Control of Waters 2545, 2525, SRO, CRO and 2767
Security Software:
Password protected for multilevel users
Logging of LC/MS acquisition parameters
Logging/time stamping of methods modification and data manipulations
Secure audit trail
QuanLynx Application Manager Withint MassLynx supports 21 CFR 11
Software Options:
MassLynx 4.1 Application Managers: ChromaLynx, FractionLynx, MarkerLynx, MetaboLynx, OpenLynx, ProfileLynx, TargetLynx, MaxEnt, Transform
Empower 2 Options: System Suitability, Chemical Structures, Gel Permeation Chromatography for Polymer Analysis
Electrospray Positive Ion Mode: 1 pg (5 µL injection of 0.2 pg/µL) reserpine at 300 µL/min flow rate yields a response >50:1 S/N-RMS**
APCI Positive Ion Mode: 1 pg (5 µL injection of 0.2 pg/µL) reserpine at 300 µL/min flow rate yields a response >50:1 S/N-RMS**
Optional Sources: Dedicated APCI IonSabre and APPI
Operating Humidity: <70%
Regulatory Approvals: IVD, NRTL, and CE
Current CPU Configuration: IBM ThinkCentre M52, 1024 MB RAM, 150 GB HDD, DVD-RAM multiburner, mouse, Windows XP, with a 20" Flat Panel Monitor
