Thanks to Engineered Simplicity™, SYNAPT G2 MS provides a high resolution exact MS/MS system with unique productivity advantages. Integrating new QuanTof technology from Waters, it is the product of our very latest innovations to deliver new levels of MS performance, productivity, and versatility to your laboratory:    

    
• IntelliStart™ Technology: for simplified system setup and automated control.    
• ACQUITY UPLC® Technology: for the highest chromatographic resolution, speed, and sensitivity.    
• QuanTof Technology: ensures you’ll capture the most complete and informative exact mass data in UPLC® timeframes, complemented by UPLC/MSE capability to capture all of the data all of the time.    
• MassLynx™ Informatics: combining the power of exact mass data and a built-in understanding of chemistry to deliver simple and rapid data interpretation and compound identification.    
• Unrivaled productivity and flexibility: allows you to customize the world’s most powerful MS system to your needs with multiple ionization options, unique system solution productivity, and future upgrade pathways.    
• Decisions made easy: thanks to Engineered Simplicity, which delivers the very highest performance and simplicity throughout your entire workflow. So experienced and novice users alike can generate high quality results. Consistently.    

     MS(E) Data Acquisition          Waters UPLC®/MSE represents a groundbreaking achievement in data acquisition. By rapidly alternating between two functions — the first acquiring exclusively low energy spectra; the second mass spectra acquired at elevated collision energies — MSE provides a generic method to comprehensively catalogue complex samples that is fully compatible with the resolution, sensitivity, and speed of UPLC separations.          Unlike conventional methods of acquisition, UPLC/MSE provides a truly comprehensive record of all detectable precursor and product ions. You won’t have to re-interrogate samples - simply acquire once and accelerate your discovery with the MassLynx™ Application Managers that are application specific.          QuanTof Technology          To equip you with an entirely new level of quantitative and qualitative capability for the most analytically challenging samples, Waters SYNAPT™ G2 incorporates a new level of performance with QuanTof™ Technology.          QuanTof is designed to provide high resolution, exact mass, and quantitative performance in a timeframe compatible with UltraPerformance LC® separations. By incorporating innovations in Tof, detector, and electronics technology, QuanTof elegantly makes leading selectivity, sensitivity, and quantitative linearity available with:    

    
• Up to 40,000 FWHM resolution    
• Linear dynamic range of up to 105    
• Exact mass (1ppm RMS)    
• Class-leading sensitivity    
• 20 spectra/sec    

     Universal Ionization Techniques for Total Flexibility          When you need to extract the maximum amount of information from a diverse range of compounds, you require the ultimate in ionization flexibility and performance.          Waters universal source technology for second-generation SYNAPT™ G2 platform enables the widest range of ionization techniques to be utilized universally across a single analytical platform. Providing the highest performance without compromise, the ionization source options are quick and easy to switch between.    

    
• ESI/APCI/ESCi®: for the analysis of polar and semi-polar analytes, when coupled with the ACQUITY UPLC® System.    
• Atmospheric Solids Analysis Probe (ASAP): for the rapid analysis of volatile and semi-volatile solid and liquid samples using atmospheric pressure ionization.    
• Nano-flow ESI: for the analysis of minute sample amounts when coupled with the nanoACQUITY UPLC® System.    
• TRIZAIC™ nanoTile™ Technology: using micro-fabricated nanoscale UPLC® separations, it utilizes sub-2 µm particle chemistries to provide the very best chromatographic performance simply and without compromise.    
• Atmospheric Pressure GC: enables rapid switching from LC/MS/MS to GC/MS/MS applications on a single instrument platform. For the analysis of volatile and semi-volatile compounds of low and intermediate polarity.    
• MALDI: ability to upgrade your system with a high performance Matrix Assisted Laser Desorption Ionization source for exact mass MALDI/MS/MS analyses. Provides easy, rapid switch to API on the same platform.