Waters - Prep SFC 100
The first commercialized supercritical fluid chromatography (SFC) system specifically designed for seamless, mass-triggered purification.
Offering seamless, mass-triggered purification, the SFC/MS Prep 100 mass-directed purification system is the automated way to improve laboratory efficiency and turn-around times by virtually eliminating solvent disposal and clean-up.
The SFC Prep 100 system utilizes high pressure CO2 as the primary mobile phase resulting in faster equilibration, lower pressure drops, solvent reduction and lower cost per sample. The process is gentle on the stationary phase, reproducible, and applicable to a wide range of compounds. The system can also be configured for UV-directed purification.
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Features of Prep SFC 100
- Faster turnaround times
- Acetonitrile-free chromatography
- Uses MS or UV to trigger fraction collection
- Scalable from analytical to preparative
- New patent-pending flow splitter and gas/liquid separator
- Automated sample handling and column switching
- MassLynx Software and FractionLynx Application Manager combined with the power of AutoPurify further streamlines the isolation and purification process
UV-Directed Purification with SFC
When fraction collection is based on UV absorbance, multiple fractions may result, requiring further analysis to determine the fraction of interest. With the SFC 100 System, run samples around the clock with unprecedented versatility and consistency. Upgrading the capability of the UV-directed system to mass-directed is available for enhanced selectivity and capability.
MS-Directed Purification with SFC
When fraction collection is triggered by mass detection, fewer fractions result since you collect only the peak containing the mass of interest. The SFC/MS 100 System provides you with the flexibility of using high-throughput selective mass-directed fraction collection from hundreds of samples.
Built around the 3100 Mass Detector, a compact, single quadrupole, atmospheric pressure ionization mass detector, the SFC/MS 100 System is designed for everyday mass-directed purification applications. The system's fluidics layout, enhanced software features, and hardware capabilities combine with OBD Column Technology for simplified operation.
For those carrying out purification in an open access environment, the Fractionlynx Application Manager combined with AutoPurify further streamlines the isolation and purification process. AutoPurify allows laboratories to automate the purification process by linking the analytical pre–screen, (performed on a separate analytical SFC system), purification, and fraction analysis (performed on a separate analytical SFC system). By using the analytical pre–screen information, the system can optimize the purification run to reduce the run time, reduce the solvent usage, and enhance the quality of the collected fraction.
General Specifications
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