Thermo Scientific - LTQ Velos Dual-Pressure Ion Trap
World's fastest and most sensitive ion trap mass spectrometer
The innovative dual-pressure ion trap and S-Lens ion optics combine to deliver increased ion transmission along with better trapping and fragmentation efficiency. The result is the fastest and most sensitive ion trap for all applications.
Continuing a commitment to providing researchers with the latest in high-performance mass spectrometers, the LTQ Velos is fully upgradeable with electron transfer dissociation (ETD) and Orbitrap™ technology to extend its capabilities even further.
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Features of LTQ Velos Dual-Pressure Ion Trap
The LTQ Velos is the latest evolution in the award winning LTQ family of linear ion trap mass spectrometers. It offers significant improvements in data acquisition rate, sensitivity, and mass resolution.
Key Features
- S-Lens ion optics increase ion transmission and shorten trap fill time, improving instrument sensitivity and data acquisition rate
- More efficient dual-pressure ion trap simultaneously increases scan speed and mass resolution
- Predictive Automatic Gain Control reduces cycle times, yielding improved data acquisition rates
- Improved sensitivity and mass resolution increase confidence in identification of low-level analytes
- Increased performance enables simultaneous identification, structural elucidation, and quantification of complex samples
- Upgradeable to the ultra-high resolution and outstanding mass accuracy of Orbitrap* technology
General Specifications
| Depth | 146.3 cm |
| Height | 141.4 cm |
| Mass Range | 200 to 4000 m/z |
| Width | 87 cm |
| Weight | 620 kg |
| Mass Spectrometer Type | Ion-Trap Mass Analyzer |
Additional Specifications
Software Features
Data System
Thermo Scientific Xcalibur processing and instrument control software
Microsoft® Office XP software package
Microsoft Windows® XP operating system
High-performance PC with Intel® microprocessor
High-resolution LCD color monitor
Scan Functions
Full-scan feature provides full-scan mass spectra for sensitive analyses and produces spectra for rapid screening of unknown compounds.
Selected ion monitoring (SIM) monitors selected ions for target compound analysis.
Full-scan MS/MS produces full-scan product ion spectra selected reaction monitoring (SRM) for a traditional LC-MS/MS quantitative analytical experiment.
MSn for multi-stage MS experiments to probe the structure of ions.
ZoomScan™, a high-resolution, full-range scan to resolve isotopic envelopes which is often used for charge state determination of peptides and ionization state determination of organometallics.
Ultra ZoomScan for ultimate resolution.
TurboScan™, an ultra-fast scan to improve signal-to-noise and sampling rate.
Exclusive Technologies
Unique, patented Automatic Gain Control (AGC) ensures that the ion trap is always filled with the optimum number of ions for any scan type.
Dynamic Exclusion™ allows acquisition of MS/MS and MSn spectra from lower intensity ion species.
WideBand Activation™ generates more structurally informative spectras.
Normalized Collision Energy™ provide reproducible data from instrument to instrument.
System Specifications
MS/MS Sensitivity
Electrospray Ionization (ESI) –2 µL of a 50 fg/µL solution of reserpine (100 femtograms total) injected at a flow of 500 µL/min will produce a minimum signal-to-noise ratio of 100:1, for the transition of the isolated protonated molecular ion at m/z 609 to the
largest two product ions, m/z 397 and m/z 448, when the mass spectrometer is operated at unit resolution in the full-scan MS/MS mode, scanning the product ion spectrum from m/z 165 – 615.
Atmospheric Pressure Chemical Ionization (APCI) – 2 µL of a 50 fg/µL solution of reserpine (100 femtograms total) injected at a flow of 500 µL/min will produce a minimum signal-to noise ratio of 100:1, for the transition of the isolated protonated molecular ion at m/z 609 to the largest two product ions, 397 and 448, when the mass spectrometer is operated at unit resolution in the full-scan MS/MS mode, scanning the product ion spectrum from m/z 165 – 615.
Installation Requirements
Power
One 230 Vac ±10.0%, 15 Amps, 50/60 Hz, single phase, with earth ground dedicated to the instrument.
120 or 230 Vac single phase, with earth ground for the data system.
Gas
One high-purity (99% pure, flow rate 15 L/min) nitrogen gas supply for the API source.
One ultra-high-purity helium gas supply (99.998% pure) with less than 1 ppm each of water, oxygen, and total hydrocarbons for the mass analyzer.
Environment
System averages 2300 W (8000 BTU/h) output when considering air conditioning needs.
Operating environment must be 15-27 °C (59-80 °F) and relative humidity must be 40-80% with no condensation.
Optimum operating temperature is 18-21 °C (65-70 °F).
Dimensions/Weight
MS: 56 cm · 79 cm · 59 cm (h · w · d)
MS: ~120 kg
Roughing pumps: 38.6 kg
Performance Specifications
Mass Range
m/z 15 – 200
m/z 50 – 2000
m/z 200 – 4000
Resolution
0.05 FWHM (full width half maximum) with Ultra ZoomScan
Scan Power
MSn, for n = 1 through 10
Analog Inputs
One (1) analog Input (0-1 V)
One (1) analog Input (0-10 V)