Thermo Scientific - LTQ XL™ Linear Ion Trap Mass Spectrometer

Manufactured by  Thermo Scientific
Follow this Equipment

Obtain more structural information for proteomics and metabolism applications. The Thermo Scientific™ LTQ...

Obtain more structural information for proteomics and metabolism applications. The Thermo Scientific™ LTQ XL™ ion trap mass spectrometer offers multiple dissociation techniques---PQD, ETD and CIDfor routine structural elucidation. PQD is a proprietary technique that eliminates low mass cut-off concerns. The result is more extensive coverage for predicted and unpredicted metabolites, and the ability to perform peptide quantification using isobaric labels.
Active Questions & AnswersAsk a Question

Recent Questions & Answers

avatar placemark

Asked byMA.TERESA

avatar placemark

Asked byXH2013

LC-MS Systems Service ProvidersView All (41)

Request Support
Features of LTQ XL™ Linear Ion Trap Mass Spectrometer

The LTQ XL ion trap MS extends the legendary MSn performance of the LTQ ion trap, incorporating more techniques to generate structural information through innovations in Thermo Scientific ion trap technology.

  • Unparalleled sensitivity and unmatched MSn spectral quality
  • Pulsed Q dissociation (PQD) for generating more fragments and extending the low mass range
  • Electron transfer dissociation (ETD) option provides sequence information not available from conventional methods
  • High-resolution isolation (HRI) enables isolation of isobaric mass peaks for cleaner MSn spectra
  • Ultra-fast polarity switching for high sensitivity analysis of unknowns
  • Automated data-dependent neutral loss for PTM and biotransformation analyses
  • Excellent charge state determinations with Ultra ZoomScan™
  • Upgradeable to Thermo Scientific™ LTQ Orbitrap XL high-resolution, accurate-mass technology

The LTQ XL supplies outstanding sensitivity and abundant structural information for:

  • Protein identification and quantitative differential expression analysis
  • Biomarker studies and PTM identification
  • Metabolite identification and quantification
  • Tissue imaging
  • High-speed LC methods

For Research Use Only. Not for use in diagnostic procedures.

General Specifications
Mass Spectrometer TypeIon-Trap Mass Analyzer
Depth 59 cm
Height56 cm
Width 79 cm
Weight120 kg
Additional Specifications

Hardware Features    
Ion Max™ API Source    
- Enhanced sensitivity and ruggedness    
- Sweep Gas™ reduces chemical noise    
- 60° interchangeable ion probe orientation    
- Removable metal ion capillary tube provides vent-free maintenance    
    
Transfer Ion Optics    
- Advanced ion guides    
- High stability and ion transmission efficiency    
    
2D Linear Quadrupole Ion Trap Mass Spectrometer    
- Optimized analyzer dimensions    
- Regulated helium flow for stable performance    
- Automatic system calibration    
- High-efficiency radial ion ejection    
    
Vacuum System    
- Differentially-pumped vacuum system    
to 10-5 Torr    
- Split-flow turbomolecular pump controlling vacuum in three regions    
- Dual rotary vacuum pump configuration    
- High-vacuum aluminum analyzer chamber    
    
Detection System    
- Patented dual conversion dynode detector    
- Two off-axis continuous dynode electron multipliers with extended dynamic range    
- Digital electronic noise discrimination    
    
Integrated Divert Valve    
- Fully-automated data system control enables user to divert the solvent front, gradient end point and any other portion of the HPLC run to waste    
- User-definable default state of the valve, either to waste or to source    
    
Integrated Syringe Pump    
- Syringe Pump allows automated infusion under data system control    
    
Options    
- ESI probe compatible with liquid flow rates of <1 µL/min to 1 mL/min, without splitting    
- APCI source compatible with liquid flow rates of 50 µL/min to 2 mL/min, without splitting    
- APCI/APPI source compatible with liquid flow rates of 50 µL/min to 2 mL/min, without splitting    
- Electron Transfer Dissociation (ETD) enabled    
- vMALDI™ ion source combines the speed of MALDI with the sensitivity and selectivity of MS/MS    
- Nanospray source supports static packed tip and dynamic nanospray experiments, compatible with liquid flow rates of 50 nL/min* to 2 µL/min    
- Metal needle option for high- and low-flow analyses    
*Lower limit is dependent on gauge of needle used    
    
System Specifications    
MS/MS Sensitivity Electrospray Ionization (ESI)  A loop injection of 2 µL of a 125 fg/µL solution of reserpine (250 femtograms total sample) at a flow of 400 µL/min of 50% isopropyl alcohol/50% water will produce a minimum signal-to-noise ratio of 100:1, for the transition of the isolated protonated molecular ion at m/z 609 to the largest two product ions, 397 and 448, when the mass spectrometer is operated at unit resolution in the full-scan MS/MS mode, scanning the product ion spectrum from m/z 165  615.    
    
Atmospheric Pressure Chemical Ionization (APCI)  A loop injection of 2 µL of a 125 fg/µL solution of reserpine (250 femtograms total sample) at a flow of 400 µL/min of 50% isopropyl alcohol/50% water will produce a minimum signal-tonoise ratio of 100:1, for the transition of the isolated protonated molecular ion at m/z 609 to the largest two product ions, 397 and 448, when the mass spectrometer is operated at unit resolution in the fullscan MS/MS mode, scanning the product ion spectrum from m/z 165  615.    
    
MSn Sensitivity Electrospray Ionization (ESI) - A loop injection of 2 µL of a 125 fg/µL solution of reserpine (250 femtograms total sample) at a flow of 400 µL/min of 50%    
isopropanol/50% water will produce a minimum signal-to-noise ratio of 25:1, for the transition of the unit isolated protonated molecular ion at m/z 609 to the product ion at m/z 397 which is further fragmented to the product ion at m/z 365, when the mass    
spectrometer is operated at unit resolution in the full-scan MS/MS mode, scanning the    
product ion spectrum from m/z 165-615.    
    
Installation Requirements    
Power    
- One 230 Vac ±10.0%, 15 Amps, 50/60 Hz, single phase, with earth ground dedicated    
to the instrument    
- 120 or 230 Vac single phase, with earth ground for the data system    
    
Gas    
- One high-purity (99% pure, flow rate 15 L/min) nitrogen gas supply for the API source    
- One ultra high-purity helium gas supply (99.998% pure) with less than 1 ppm each of water, oxygen, and total hydrocarbons for the mass analyzer    
    
Environment    
- System averages 2300 W (8000 Btu/h) output when considering air conditioning needs    
- Operating environment must be 15-27 °C (59-80 °F) and relative humidity must be 40-80% with no condensation    
- Optimum operating temperature is 18-21 °C (65-70 °F)    
    
Weight: Two roughing pumps: 38.6 kg each    
    
Performance Specifications    
Mass Range    
m/z 15  200    
m/z 50  2000    
m/z 200  4000    
    
Resolution    
Down to 0.05 FWHM (full width half maximum) with Ultra ZoomScan    
    
Polarity Switching    
100 msec between positive and negative    
    
MS Scan Power    
MSn, for n = 1 through 15    
    
Contact Closure    
Start In/Out    
Start Out is programmable    
    
Analog Inputs    
One (1) analog Input (0-1 V)    
One (1) analog Input (0-10 V)

Looking for

Thermo Scientific - LTQ XL™ Linear Ion Trap Mass Spectrometer?

Shop on LabX.com