Agilent Technologies - 1290 Infinity Autosampler

Manufactured by  Agilent Technologies
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Fast Sample Injection with Highest Precision and Lowest Carryover

The 1290 Infinity Autosampler is part of the 1290 Infinity LC system that is compatible with operating pressures up to 1200 bar. It features the next-generation flow-through design for high precision injection of both large and small volumes without the need to change sample loops. Only the injected volume is required from the sample and no valuable sample is wasted for flushing. Inert materials in the metering device seal and needle seat as well as reduced hydraulic volumes achieve extremely low carryover. A new module, the 1290 Infinity Flexible Cube, combines seamlessly with the autosampler for infinite injection flexibility. The Flexible Cube facilitates fixed-loop injection mode for ultra-fast cycle times as well as automatic backflushing of the autosampler’s needle seat for lowest carryover yet.
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Features of 1290 Infinity Autosampler
  • Next generation flow-through design with ultra low system volume for operation up to 1200 bar    
  • Highest injection precision for both large and small volumes without changing loops    
  • No waste of valuable sample for flushing    
  • Short injection cycles for higher productivity through overlapped injections    
  • Best carryover performance through inert seal and needle seat material as well as backflush of needle seat (requires 1290 Infinity Flexible Cube)    
  • New cartridge loop for ultimate ease-of-use    
  • Flexible and convenient sample handling with different types of sample containers such as well-plates and vials – process up to 768 samples unattended with 384-well plates    
  • Peltier temperature control from 4 to 40 °C for thermally labile samples (requires 1290 Infinity Thermostat)
General Specifications

There are no General Specifications available.

Additional Specifications

Communications:    
Controller-area network (CAN). RS232C, APG-remote standard,    
optional four external contact closures and BCD vial number output    
Safety features:    
Leak detection and safe leak handling, low voltages in maintenance areas, error detection and display    
Injection precision:    
<0.25% from 5-40 µL    
<0.5% from 2-5 µL    
<0.7% from 0.5-2µL    
Injection accuracy: ± 1% (10 µL, n=10)    
Sample viscosity range:    
0.2 - 5 cp    
Sample capacity:    
2 × well-plates (MTP) + 10 × 2 ml vials    
108 × 2-mL vials in2 × 54 vial plate plus 10 additional 2-mL vials    
30 × 6-mL vials in 2 x 15 vial plate plus 10 additional 2-mL vials    
54 Eppendorf tubes (0.5/1.5/2.0mL) in 2 × 27 Eppendorf tube plate    
Compatible with the Agilent 1200 Series Sample Capacity Extension for further expansion of the sample capacity    
    
Injection cycle time    
Typically < 21 s using following standard conditions:    
Default draw speed: 200 µL/min    
Default eject speed: 200 µL/min    
Injection volume: 5 µL    
    
Carryover    
Typically < 0.004 % using the following condition:    
Column: 2.1 x 50 mm ZORBAX SB C18, 1.8 µm    
Sample: Chlorhexidine dissolved in water + 0.1 % TFA    
Mobile phase: water + 0.05 % TFA, acetonitrile + 09.045 % TFA    
Flow rate: 0.5 mL/min    
Gradient: at 0 min 30 % B, at 3 min 60 % B    
Injection volume: 1 µL external needle wash with water + 0.1 % TFA, draw and inject speed = 100 µL/min    
Column temperature: 50 °C    
MSD API-ES positive: SIM ion 505.30    
Fragmentor: 70    
Gas temperature: 250 °C    
Drying gas: 12 L/min    
Vcap: 3000V    
    
GLP features:    
Early maintenance feedback (EMF), electronic records of maintenance and errors

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