Malvern Panalytical - Zetasizer µV
A highly sensitive batch DLS instrument and a powerful SEC-LS detector, in a single package.
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Features of Zetasizer µV
Connect the Zetasizer µV to your SEC system using standard chromatography tubing
- Measure protein size and molecular weight
- No column calibration
- Determine protein oligomeric state
- Measure the polydispersity of each peak
- Low volume 8µL flow cell
- Compatible with any SEC system
Simply remove the flow cell and insert a cuvette
- No calibration required
- Minimum of 2µL of sample
- Absolute size measurement
- Sensitive detection of the presence of aggregates
- Screen buffers for crystallisation conditions
- Determine protein melting point or aggregation temperature
- Measure molecular weight and second virial coefficient
General Specifications
Depth | 410 mm |
Height | 170 mm |
Width | 350 mm |
Weight | 14 kg |
Additional Specifications
Temperature control range: 2°C - 90°C +/- 0.1°C*
Measurement angle: 90°
Condensation control: Purge facility using dry air
Standard laser: 60mW, 830nm
Correlator: Min. sample time 480ns, max. 3600s. 264 channels
Specifications for operation in cuvette mode
Size range (radius): 0.15nm - 1 micron**
Minimum sample volume: 2µL
Sensitivity: 0.1mg/mL of 15kDa protein
Molecular weight range (estimated from hydrodynamic diameter): 342Da to >106Da
Molecular weight range (calculated using Debye plot): 980Da to >106Da
Minimum sample volume: 2µL
Results output: Molecular size, molecular weight, A2, size distribution
Specifications for operation in chromatography detector mode
Flow cell volume: 8µL
Molecular weight range: 106Da
Results output: Mn, Mw, Mz, Mp, Mw/Mn, Rh, Weight Fraction, Concentration, dn/dc, dA/dc. A2